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The cell biology of glycosphingolipids
Seminars in Cell & Developmental Biology, 2004 Glycosphingolipids, a family of heterogeneous lipids with biophysical properties conserved from fungi to mammals, are key components of cellular membranes. Because of their tightly packed backbone, they have the ability to associate with other sphingolipids and cholesterol to form microdomains called lipid rafts, with which a variety of proteins ...
Degroote, S. +2 more
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Glycosphingolipids of human thyroid
Lipids, 1974 AbstractGlycosphingolipids were isolated from total lipids of female and male human thyroids by alkaline hydrolysis, silicic acid, diethylaminoethyl‐celluose and thin layer chromatography and analyzed by gas liquid chromatography. On the basis of their mobility in two dimensions on thin layer chromatography, IR analysis, and of sugar molar ratio, four ...
Karli, J.N., Levis, G.M.
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Glycosphingolipids and drug resistance
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2006 Drug resistance, an all too frequent characteristic of cancer, represents a serious barrier to successful treatment. Although many resistance mechanisms have been described, those that involve membrane-resident proteins belonging to the ABC (ATP binding cassette) transporter superfamily are of particular interest.
Gouaze-Andersson, Valerie +1 more
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Micellar properties of glycosphingolipids in aqueous media.
Journal of Lipid Research, 1984 The aggregation properties of neutral glycosphingolipids and gangliosides were investigated by ultracentrifugal sedimentation and gel permeation chromatography. Initially, glycosphingolipids in buffer formed high molecular aggregates.
B Ulrich-Bott, H Wiegandt
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Glycosphingolipid Functions [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 The combination of carbohydrate and lipid generates unusual molecules in which the two distinctive halves of the glycoconjugate influence the function of each other. Membrane glycolipids can act as primary receptors for carbohydrate binding proteins to mediate transmembrane signaling despite restriction to the outer bilayer leaflet.
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Characterization of moose intestinal glycosphingolipids [PDF]
, 2015 As a part of a systematic investigation of the species-specific expression of glycosphingolipids, acid and non-acid glycosphingolipids were isolated from three small intestines and one large intestine of the moose (Alces alces).
John Benktander +13 more
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Biochemical studies on sphingolipids of Artemia franciscana: novel neutral glycosphingolipids[S]
Journal of Lipid Research, 2011 Neutral glycosphingolipids containing one to six sugars in their oligosaccharide chains have been isolated from cysts of the brine shrimp Artemia franciscana.
Hisao Kojima +5 more
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FEBS Open Bio, 2023 Intracellular organelles carry out many of their functions by engaging in extensive interorganellar communication through specialized membrane contact sites (MCSs) formed where two organelles tether to each other or to the plasma membrane (PM) without ...
Jason Andrew Weesner +3 more
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Role of Globotriaosylceramide in Physiology and Pathology
Frontiers in Molecular Biosciences, 2022 At first glance, the biological function of globoside (Gb) clusters appears to be that of glycosphingolipid (GSL) receptors for bacterial toxins that mediate host-pathogen interaction.
Ana Beatriz Celi +6 more
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PLoS ONE, 2011 Enterotoxigenic F4-fimbriated Escherichia coli is associated with diarrheal disease in neonatal and postweaning pigs. The F4 fimbriae mediate attachment of the bacteria to the pig intestinal epithelium, enabling an efficient delivery of diarrhea-inducing
Annelies Coddens +6 more
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