Results 11 to 20 of about 18,580 (229)
Glycosphingolipids of human thyroid
Lipids, 1974 AbstractGlycosphingolipids were isolated from total lipids of female and male human thyroids by alkaline hydrolysis, silicic acid, diethylaminoethyl‐celluose and thin layer chromatography and analyzed by gas liquid chromatography. On the basis of their mobility in two dimensions on thin layer chromatography, IR analysis, and of sugar molar ratio, four ...
Karli, J.N., Levis, G.M.
core +5 more sources
The cell biology of glycosphingolipids [PDF]
Seminars in Cell & Developmental Biology, 2004 Glycosphingolipids, a family of heterogeneous lipids with biophysical properties conserved from fungi to mammals, are key components of cellular membranes. Because of their tightly packed backbone, they have the ability to associate with other sphingolipids and cholesterol to form microdomains called lipid rafts, with which a variety of proteins ...
Degroote, S. +2 more
core +6 more sources
Ciliary Membrane Lipid Homeostasis in Health and Disease. [PDF]
Adv Sci (Weinh)This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Huang Z, Liu YY, Sun H, Liu P.
europepmc +2 more sources
Unraveling A4GALT Mechanism and Its Modulation With Adamantyl-Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies. [PDF]
Angew Chem Int Ed EnglA 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
de Koster N +13 more
europepmc +3 more sources
Lyso-glycosphingolipids: presence and consequences [PDF]
, 2020 Lyso-glycosphingolipids are generated in excess in glycosphingolipid storage disorders. In the course of these pathologies glycosylated sphingolipid species accumulate within lysosomes due to flaws in the respective lipid degrading machinery. Deacylation
Ferraz, M.J. +3 more
core +1 more source
Studies on glycosphingolipids in infection, immunity and differentiation [PDF]
, 2015 Cell surface glycoconjugates play a role in many biological processes such as responses to microbial infections, cell-cell interactions, differentiation, and inflammatory responses.
Benktander, John
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Studies on glycosphingolipids in regenerative medicine [PDF]
, 2014 Regenerative medicine, including stem cell based therapies and xenotransplantation, is a new and developing field that aims to restore normal function in end stage cell/organ failure.
Barone, Angela
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Glycosphingolipid Functions [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 The combination of carbohydrate and lipid generates unusual molecules in which the two distinctive halves of the glycoconjugate influence the function of each other. Membrane glycolipids can act as primary receptors for carbohydrate binding proteins to mediate transmembrane signaling despite restriction to the outer bilayer leaflet.
openaire +3 more sources
Characterization of moose intestinal glycosphingolipids [PDF]
, 2015 As a part of a systematic investigation of the species-specific expression of glycosphingolipids, acid and non-acid glycosphingolipids were isolated from three small intestines and one large intestine of the moose (Alces alces).
John Benktander +13 more
core +1 more source
Biochemical studies on sphingolipids of Artemia franciscana: novel neutral glycosphingolipids[S]
Journal of Lipid Research, 2011 Neutral glycosphingolipids containing one to six sugars in their oligosaccharide chains have been isolated from cysts of the brine shrimp Artemia franciscana.
Hisao Kojima +5 more
doaj +1 more source