Results 111 to 120 of about 7,450 (200)

Modulation of Enterohaemorrhagic Escherichia coli Survival and Virulence in the human Gastrointestinal Tract [PDF]

, 2018
Enterohaemorrhagic Escherichia coli (EHEC) is a major foodborne pathogen responsible for human diseases ranging from diarrhoea to life-threatening complications.
Blanquet-Diot, Stéphanie, Desvaux, Mickaël, Etienne-Mesmin, Lucie, Jubelin, Grégory, Muniesa, Maite, Schuller, Stephanie   +5 more
core   +4 more sources

Verotoxin A Subunit Protects Lymphocytes and T Cell Lines against X4 HIV Infection in Vitro

Toxins, 2012
Our previous genetic, pharmacological and analogue protection studies identified the glycosphingolipid, Gb3 (globotriaosylceramide, Pk blood group antigen) as a natural resistance factor for HIV infection. Gb3 is a B cell marker (CD77), but a fraction of
Pei Lin Shi, Beth Binnington, Darinka Sakac, Yulia Katsman, Stephanie Ramkumar, Jean Gariepy, Minji Kim, Donald R. Branch, Clifford Lingwood   +8 more
doaj   +1 more source

Electrocardiographic Changes and Arrhythmia in Fabry Disease

Frontiers in Cardiovascular Medicine, 2016
Fabry disease is an X-chromosome-linked lysosomal storage disease characterized by a deficient activity or, in most males, absence of the enzyme alpha-galactosidase A (a-Gal A) leading to systemic, primary lysosomal accumulation of globotriaosylceramide (
Mehdi eNamdar
doaj   +1 more source

Role of TNF-α in the Mechanisms Responsible for Preterm Delivery Induced by Stx2 in Rats [PDF]

, 2013
Shiga toxin-producing Escherichia coli (STEC) infections could be one of the causes of fetal morbimortality in pregnant women. We have previously reported that Shiga toxin type 2 (Stx2) causes preterm delivery in pregnant rats. In this study, we evaluate
Aisemberg, Burdet, Burdet, Endo, Frank, Fraser, Gianantonio, Goldstein, Gravett, Grigsby, Ibarra, Inglis, Karmali, Kilkenny, Landoni, Lingwood, Lingwood, Louise, Louise, McGrath, Paton, Peltier, Raghupathy, Renaud, Repetto, Ribeiro, Richardson, Rivas, Romero, Sato, Scully, Shiau, Silen, Silver, Steele, Strauss, Tesh   +36 more
core   +1 more source

Biochemical and clinical analysis of accumulated glycolipids in symptomatic heterozygotes of angiokeratoma corporis diffusum (Fabry's disease) in comparison with hemizygotes.

Journal of Lipid Research, 1990
Angiokeratoma corporis diffusum (Fabry's disease) is an X-linked disorder of glycosphingolipid catabolism. Heterozygous females, although usually asymptomatic, are occasionally as severely afflicted as hemizygous males; recently we identified a ...
I Hozumi, M Nishizawa, T Ariga, T Miyatake   +3 more
doaj   +1 more source

Genetic variants associated with gastrointestinal symptoms in Fabry disease. [PDF]

, 2016
Gastrointestinal symptoms (GIS) are often among the earliest presenting events in Fabry disease (FD), an X-linked lysosomal disorder caused by the deficiency of α-galactosidase A.
Agapito, Giuseppe, Altomare, Federica, Arbitrio, Mariamena, Borrelli, Osvaldo, Concolino, Daniela, Di Martino, Maria Teresa, Guzzi, Pietro Hiram, Nicoletti, Angela, Pensabene, Licia, Pisani, Antonio, Riccio, Eleonora, Sanseviero, Maria Teresa, Scionti, Francesca, Sestito, Simona, Talarico, Valentina   +14 more
core   +1 more source

Evidence for a role of sphingosine-1 phosphate in cardiovascular remodelling in Fabry disease [PDF]

, 2017
Aims A hallmark of Fabry disease is the concomitant development of left-ventricular hypertrophy and arterial intima-media thickening, the pathogenesis of which is thought to be related to the presence of a plasmatic circulating growth-promoting factor ...
Barbey, Frédéric, Bekri, Soumeya, Brakch, Noureddine, Correvon, Magali, Dormond, Olivier, Golshayan, Dela, Mazzolai, Lucia, Steinmann, Beat   +7 more
core  

Delphi consensus on the current clinical and therapeutic knowledge on Anderson-Fabry disease [PDF]

, 2014
BACKGROUND: Management of Anderson-Fabry disease (AFD) is contentious, particularly regarding enzyme replacement therapy (ERT). We report results of a Delphi consensus panel on AFD management.
Antuzzi, D., Bembi, B., Benso, A., Carraro, G., Chimenti, C., Colla, L., Concolino, D., Cuonzo, M. T., Degennaro, E., Del Rosso, G., Diomedi, M., Feliciani, C., Feriozzi, S., Ficcadenti, A., Frustaci, A., Gnarra, M., Maccarone, M., Mancuso, M., Matucci, A., Mignani, R., Musumeci, B., Nencini, P., Parini, R., Piga, S., Pisani, A., Re, F., Salviati, A., Spada, M., Vultaggio, A., Zachara, E., Zedde, M. L., Zoli, P. G.   +31 more
core   +1 more source

Commentary on ‘Lentivirus‐mediated gene therapy for Fabry disease: 5‐year end‐of‐study results from the Canadian FACTS trial’

Clinical and Translational Discovery, Volume 5, Issue 2, April 2025.
Alessandro Rossi, Nicola Brunetti‐Pierri   +1 more
wiley   +1 more source

Renal globotriaosylceramide deposits for Fabry disease linked to uncertain pathogenicity gene variant c.352C>T/p.Arg118Cys: A family study

Molecular Genetics & Genomic Medicine, 2019
Background Fabry disease (FD) has an extensive phenotypic expression associated with GLA gene variants. The GLA gene variant c.352C>T/p.Arg118Cys was considered with uncertain pathogenicity because of the finding of high residual alpha‐galactosidase A (α‐
Magdalena Cerón‐Rodríguez, Guillermo Ramón‐García, Edgar Barajas‐Colón, Isidro Franco‐Álvarez, Juan L. Salgado‐Loza   +4 more
doaj   +1 more source