Results 181 to 190 of about 7,450 (200)

ChemInform Abstract: A Practical and Enantioselective Synthesis of Glycosphingolipids and Related Compounds. Total Synthesis of Globotriaosylceramide (Gb3).

ChemInform, 1989
K. C. Nicolaou, Thomas J. Caulfield, Hiromi Kataoka, T. KUMAZAWA   +3 more
semanticscholar   +3 more sources

Tu-P7:239 Cellular and tissue distribution of globotriaosylceramide (GB3) in fabry disease (FD)

Atherosclerosis Supplements, 2006
Hassan Askari, David E. Kleiner, Christine R. Kaneski, Linda E. Spollen, Raphael Schiffmann   +4 more
semanticscholar   +3 more sources

Globotriaosylceramide (Gb3) induces a proinflammatory cytokine profile in dendritic cells and macrophages: Consequences for Fabry disease

Molecular Genetics and Metabolism, 2013
Pablo N. De Francesco, Juan M. Mucci, Romina Ceci, Paula Rozenfeld   +3 more
semanticscholar   +3 more sources

Efficient generation of useful monoclonal antibodies reactive with globotriaosylceramide using knockout mice lacking Gb3/CD77 synthase

Glycoconjugate Journal, 2011
Efficient generation of useful monoclonal antibodies (mAbs) with high performance in cancer therapeutics has been expected. Generation of mAbs reactive with globotriaosylceramide (Gb3/CD77) was compared between A/J mice and Gb3/CD77 synthase-deficient (A4GalT-knockout) mice by immunizing Gb3-liposome. Specificity and functions of established antibodies
Yuji Kondo, Noriyo Tokuda, Keiko Furukawa, Reiko Ando, Makoto Uchikawa, Qing Zhang, Fan Xiaoyan, Koichi Furukawa   +7 more
openalex   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

High‐Risk Screening for Fabry Disease: Analysis by Tandem Mass Spectrometry of Globotriaosylceramide (Gb₃) in Urine Collected on Filter Paper

Current Protocols in Human Genetics, 2017
AbstractFabry disease is a complex, panethnic lysosomal storage disorder. It is characterized by the accumulation of glycosphingolipids in tissues, organs, the vascular endothelium, and biological fluids. The reported incidence in different populations is quite variable, ranging from 1:1400 to 1:117,000.
Christiane, Auray-Blais, Pamela, Lavoie, Michel, Boutin, Mona, Abaoui   +3 more
openaire   +3 more sources

Analysis of globotriaosylceramide (Gb 3 ) isoforms/analogs in unfractionated leukocytes, B lymphocytes and monocytes from Fabry patients using ultra-high performance liquid chromatography/tandem mass spectrometry

Analytica Chimica Acta, 2018
Fabry disease is an X-linked lysosomal storage disorder with marked variability in the phenotype and genotype. Glycosphingolipids such as globotriaosylceramide (Gb3) isoforms/analogs, globotriaosylsphingosine (lyso-Gb3) and analogs, and galabiosylceramide (Ga2) isoforms/analogs may accumulate in biological fluids and different organs.
Amanda, Toupin, Pamela, Lavoie, Marie-Françoise, Arthus, Mona, Abaoui, Michel, Boutin, Carole, Fortier, Claudia, Ménard, Daniel G, Bichet, Christiane, Auray-Blais   +8 more
openaire   +3 more sources

A Verotoxin 1 B Subunit-Lambda CRO Chimeric Protein Specifically Binds Both DNA and Globotriaosylceramide (Gb3) to Effect Nuclear Targeting of Exogenous DNA in Gb3 Positive Cells

Experimental Cell Research, 2001
Inefficient nuclear incorporation of foreign DNA remains a critical roadblock in the development of effective nonviral gene delivery systems. DNA delivered by traditional protocols remains within endosomal/lysosomal vesicles, or is rapidly degraded in the cytoplasm.
Linda M. Facchini, Clifford A. Lingwood
openalex   +3 more sources

Globotriaosylceramide (Gb3/CD77) is synthesized and surface expressed by bovine lymphocytes upon activation in vitro

Veterinary Immunology and Immunopathology, 2001
Neutral glycosphingolipids (GSLs) are considered activation markers on human lymphocytes, which are fundamental for studying the immune system. For cattle, only a limited number of activation markers has yet been identified. We recently showed that Shiga toxin 1, known to use globotriaosylceramide (Gb(3) syn.
Christian Menge, Ivonne Stamm, Manfred Wuhrer, Rudolf Geyer, Lothar H. Wieler, G. Baljer   +5 more
openalex   +3 more sources

Lectin-Based Substrate Detection in Fabry Disease Using the Gb3-Binding Lectins StxB and LecA

International Journal of Molecular Sciences
Fabry disease, the second most common lysosomal storage disorder, is caused by a deficiency of α-galactosidase A (α-Gal A), which leads to an accumulation of glycosphingolipids (GSL), mainly globotriaosylceramide (also known as Gb3).
Serap Elçin-Guinot, S. Lagies, Yoav Avi-Guy, Daniela Neugebauer, Tobias B. Huber, C. Schell, Bernd Kammerer, Winfried Römer   +7 more
semanticscholar   +1 more source

The lipid globotriaosylceramide promotes germinal center B cell responses and antiviral immunity

Science
Influenza viruses escape immunity owing to rapid antigenic evolution, which requires vaccination strategies that allow for broadly protective antibody responses.
Pankaj Sharma, Xiaolong Zhang, Kevin Ly, Yuxiang Zhang, Yu Hu, Adam Yongxin Ye, Jianqiao Hu, Ji Hyung Kim, Mumeng Lou, Chong Wang, Quinton Celuzza, Yuji Kondo, Keiko Furukawa, David R. Bundle, Koichi Furukawa, Frederick W. Alt, F. Winau   +16 more
semanticscholar   +1 more source