Results 131 to 140 of about 36,167 (318)

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

The Star Clusters as Links between Galaxy Evolution and Star Formation Project. I. Numerical Method

open access: yesThe Astrophysical Journal
Stellar clusters are critical constituents within galaxies: They are the result of highest-density star formation, and through their spatially and temporally correlated feedback, they regulate their host galaxy evolution.
Marta Reina-Campos   +3 more
doaj   +1 more source

HPDL Variant Type Correlates With Clinical Disease Onset and Severity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recently, a mitochondrial encephalopathy due to biallelic HPDL variants was described, associated with a broad range of clinical manifestations ranging from severe, infantile‐onset neurodegeneration to adolescence‐onset hereditary spastic paraplegia. HPDL converts 4‐hydroxyphenylpyruvate acid (4‐HPPA) into 4‐hydroxymandelate (4‐HMA),
Eun Hye Lee   +19 more
wiley   +1 more source

Star-to-Star Abundance Variations among Bright Giants in the Mildly Metal-poor Globular Cluster M4 [PDF]

open access: bronze, 1999
Inese I. Ivans   +6 more
openalex   +1 more source

Hot Stars in Globular Clusters

open access: yes, 1998
26 pages, 11 Postscript figures, to appear in Reviews in Modern Astronomy (Astronomische Gesellschaft)
openaire   +2 more sources

Variable stars in the globular cluster NGC 2419

open access: yes, 2005
We have used DOLORES at the TNG to obtain B,V time series photometry of NGC 2419, one of the most distant and bright clusters in the Galactic halo. These data will be used to study its variable star population in order to check whether the cluster could be the relic of an extragalactic system accreted by the Milky Way.
Ripepi, V.   +9 more
openaire   +3 more sources

Compound Heterozygous MRPS14 Variants Associated With Leigh Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT MRPS14 (uS14m) is a nuclear‐encoded ribosomal protein important for mitochondria‐specific translation. To date, only a single individual with a recessive MRPS14‐related disorder (also known as COXPD38) has been reported. We report an additional subject possessing novel compound heterozygous MRPS14 variants (p.Asp37Asn, p.Asn60Asp). The subject
Maria Gabriela Otero   +15 more
wiley   +1 more source

Pathway Analyses of Inherited Neuropathies Identify Putative Common Mechanisms of Axon Degeneration

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Inherited neuropathies (IN) are associated with over 100 different genetic mutations presenting with a variety of phenotypes. This complexity suggests multiple pathways may converge onto a limited number of downstream pathways to effect axonal injury.
Christopher R. Cashman   +2 more
wiley   +1 more source

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