Results 1 to 10 of about 66,871 (257)

Improved Assessment of Globularity of Protein Structures and the Ellipsoid Profile of the Biological Assemblies from the PDB [PDF]

open access: yesBiomolecules, 2023
In this paper, we present an update to the ellipsoid profile algorithm (EP), a simple technique for the measurement of the globularity of protein structures without the calculation of molecular surfaces.
Mateusz Banach
doaj   +3 more sources

Assessment of Globularity of Protein Structures via Minimum Volume Ellipsoids and Voxel-Based Atom Representation

open access: yesCrystals, 2021
A computer algorithm for assessment of globularity of protein structures is presented. By enclosing the input protein in a minimum volume ellipsoid (MVEE) and calculating a profile measuring how voxelized space within this shape (cubes on a uniform grid)
Mateusz Banach
doaj   +2 more sources

Chromosomal rearrangements and protein globularity changes in Mycobacterium tuberculosis isolates from cerebrospinal fluid [PDF]

open access: yesPeerJ, 2016
Background Meningitis is a major cause of mortality in tuberculosis (TB). It is not clear what factors promote central nervous system invasion and pathology but it has been reported that certain strains of Mycobacterium tuberculosis (Mtb) might have ...
Seow Hoon Saw   +4 more
doaj   +3 more sources

Brain asymmetry in the white matter making and globularity

open access: yesFrontiers in Psychology, 2015
Recent studies from the field of language genetics and evolutionary anthropology have put forward the hypothesis that the emergence of our species-specific brain is to be understood not in terms of size, but in light of developmental changes that gave ...
Constantina eTheofanopoulou
doaj   +2 more sources

How round is a protein? Exploring protein structures for globularity using conformal mapping.

open access: yesFrontiers in Molecular Biosciences, 2014
We present a new algorithm that automatically computes a measure of the geometric difference between the surface of a protein and a round sphere. The algorithm takes as input two triangulated genus zero surfaces representing the protein and the round ...
Joel eHass, Patrice eKoehl
doaj   +2 more sources

Globularity and language-readiness: Generating new predictions by expanding the set of genes of interest

open access: yesFrontiers in Psychology, 2014
This study builds on the hypothesis put forth in Boeckx and Benitez-Burraco (2014), according to which the developmental changes expressed at the levels of brain morphology and neural connectivity that resulted in a more globular braincase in our species
Cedric eBoeckx   +1 more
doaj   +2 more sources

No Country for Oldowan Men: Emerging Factors in Language Evolution

open access: yesFrontiers in Psychology, 2019
Language evolution has long been researched. I will review a number of broad, emerging research directions which arguably have the potential to contribute to our understanding of language evolution.
Elliot Murphy
doaj   +2 more sources

The shape of the language-ready brain

open access: yesFrontiers in Psychology, 2014
Our core hypothesis is that the emergence of our species-specific language-ready brain ought to be understood in light of the developmental changes expressed at the levels of brain morphology and neural connectivity that occurred in our species after the
Cedric Arnaud Boeckx   +2 more
doaj   +2 more sources

Changes in infant head shape: Developmental trends during the first year of life and secular changes observed in recent years. [PDF]

open access: yesPLoS ONE
The cephalic index (CI), defined as the percentage of head width to length, has been used in multiple studies. However, CI only provides 2D information, and comprehensive methods to assess the 3D cranial shape are yet to be established.
Eujin Lee   +4 more
doaj   +2 more sources

Deciphering Chemical Rules for Drug Penetration into Strongyloides [PDF]

open access: yesPharmaceutics
Background: Strongyloidiasis, a parasitic infection, presents a significant public health challenge in tropical regions due to the limited repertoire of effective treatments.
Miguel Marín   +5 more
doaj   +2 more sources

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