Results 151 to 160 of about 113,146 (196)
ABSTRACT Background Replacement therapy with modified‐release hydrocortisone capsules (MRHC) restores the physiological circadian cortisol rhythm in congenital adrenal hyperplasia (CAH). Aims To determine the relative bioavailability of MRHC and evaluate an optimal protocol to switch CAH patients from standard therapy to MRHC.
Richard John M. Ross+15 more
wiley +1 more source
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak+4 more
wiley +1 more source
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton+4 more
wiley +1 more source
The findings demonstrated no significant difference in MACE between the sirolimus‐treated and untreated groups (hazard ratio, 1.40; 95% confidence interval, .77–2.55), despite a higher incidence of dyslipidaemia in the sirolimus‐treated group. However, subgroup analysis indicated an increased MACE risk in KTRs with pre‐transplant congestive heart ...
Jinhyun Park+8 more
wiley +1 more source
The impact of immature granulocytes on the outcome of patients with decompensated cirrhosis
Immature granulocyte (IG) count and percentage had a predictive role in patients with decompensated cirrhosis, making them an objective and easily available marker of prognosis for this group of patients. In addition, IG percentage was the only factor independently associated with transplant‐free survival.
Magdalini Adamantou+10 more
wiley +1 more source
Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina+8 more
wiley +1 more source
ABSTRACT Introduction Myeloablative conditioning (MAC) for acute myeloid leukemia (AML) improves disease control by reducing relapse risk but is associated with higher non‐relapse mortality (NRM). Reduced‐intensity conditioning (RIC) aims to minimize toxicity but raises concerns about higher relapse rates.
Ahmed Alnughmush+12 more
wiley +1 more source