Results 211 to 220 of about 31,171 (253)
British Journal of Clinical Pharmacology, EarlyView.Abstract In solid organ transplantation (SOT), biologicals such as recombinant therapeutic proteins, monoclonal antibodies, fusion proteins and conjugates are increasingly used for immunosuppression, desensitization, ABO (blood group) incompatibility, antibody‐mediated rejections and atypical haemolytic uremic syndrome.
Stein Bergan, Nils Tore Vethe
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British Journal of Haematology, EarlyView.Proposed management of newly diagnosed Philadelphia chromosome‐positive (Ph+) acute lymphoblastic leukaemia (ALL) in transplant‐eligible patients. Suggested considerations when deciding the treatment pathway available to a newly diagnosed Ph+ ALL patient that would be deemed transplant eligible. Summary Acute lymphoblastic leukaemia (ALL) in 20%–30% of
Naranie Shanmuganathan, Andrew Grigg
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THE GLOBULINS OF THE JACK BEAN (CANAVALIA ENSIFORMIS)
, 1925 James B. Sumner, V. A. Graham
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British Journal of Haematology, EarlyView.The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an
Flore Sicre de Fontbrune +20 more
wiley +1 more source
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
British Journal of Pharmacology, EarlyView.Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
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Clinical Endocrinology, EarlyView.ABSTRACT Objective Sleep problems like obstructive sleep apnea (OSA) are common in polycystic ovary syndrome (PCOS), although the underlying mechanisms are not well understood. We aimed to determine the prevalence of sleep problems, synthesise and appraise studies analysing the associations between serum sex hormones, sex hormone‐binding globulin (SHBG)
Nur K. Abdul Jafar +4 more
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Clinical Endocrinology, EarlyView.ABSTRACT Introduction Saliva hormone measurement is increasingly being applied in everyday clinical practice. In relation to salivary cortisone measurement, there is a particular advantage, with minimal chance of cross‐reaction with prescribed glucocorticoids and greater convenience.
Mathilde Mordaunt +10 more
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Clinical Endocrinology, EarlyView.ABSTRACT Objective To describe the bioactivity of circulating androgens during pubertal transition as determined by an in vitro bioassay assessing androgen receptor (AR) activation, and to compare these findings with circulating concentrations of total testosterone (total T) measured by LC‐MS/MS.
Andrés Felipe Ø. Fritzbøger +10 more
wiley +1 more source
European Journal of Clinical Investigation, EarlyView.The findings demonstrated no significant difference in MACE between the sirolimus‐treated and untreated groups (hazard ratio, 1.40; 95% confidence interval, .77–2.55), despite a higher incidence of dyslipidaemia in the sirolimus‐treated group. However, subgroup analysis indicated an increased MACE risk in KTRs with pre‐transplant congestive heart ...
Jinhyun Park +8 more
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The impact of immature granulocytes on the outcome of patients with decompensated cirrhosis
European Journal of Clinical Investigation, EarlyView.Immature granulocyte (IG) count and percentage had a predictive role in patients with decompensated cirrhosis, making them an objective and easily available marker of prognosis for this group of patients. In addition, IG percentage was the only factor independently associated with transplant‐free survival.
Magdalini Adamantou +10 more
wiley +1 more source