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Thin glomerular basement membrane disease.
Journal of nephrology, 2000The term thin glomerular basement membrane disease (TBMD) refers to a condition characterised by thinning of the GBM at electron microscopy examination and, clinically, by isolated hematuria, frequently occurring in other family members, with no extra-renal manifestations.
FRASCA' GM., ONETTI-MUDA A., RENIERI A.
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Thin Glomerular Basement Membranes
American Journal of Kidney Diseases, 1999Fig 2. The diagnosis of thin basement membranes is made by electron microscopy. There is diffuse attenuation of the glomerular basement membrane, as illustrated here. In adults, basement membrane thickness less than 250 nm is indicative of thin basement membranes.
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Glomerular Basement Membrane Antigens
1983In experimental nephritis produced by the administration of nephrotoxic serum, there is in vivo localization of heterologous immunoglobulin antibodies in a smooth linear pattern along the glomerular basement membrane (GBM) (Hammer and Dixon, 1963). Nephrotoxic serum, produced by immunization with isolated GBM, reacts in vitro by fixing not only to GBM,
Alfred J. Fish +3 more
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Genetic Disorders of Glomerular Basement Membranes
Nephron Clinical Practice, 2010This review provides current information about glomerular disorders that arise directly from inherited abnormalities in extracellular matrix proteins intrinsic to the glomerular basement membrane (Alport syndrome, thin basement membrane nephropathy, HANAC syndrome and Pierson syndrome).
Clifford E, Kashtan, Yoav, Segal
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Clinical and Experimental Nephrology, 2019
Thin basement membrane nephropathy (TBMN) is diagnosed by diffuse thinning of the glomerular basement membrane (GBM) without any clinical and pathologic findings of Alport syndrome and the other renal diseases. TBMN is characterized clinically by benign familial hematuria but rarely develops into end-stage renal disease.In 27 cases of biopsy-proven ...
Yusuke Kajimoto +7 more
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Thin basement membrane nephropathy (TBMN) is diagnosed by diffuse thinning of the glomerular basement membrane (GBM) without any clinical and pathologic findings of Alport syndrome and the other renal diseases. TBMN is characterized clinically by benign familial hematuria but rarely develops into end-stage renal disease.In 27 cases of biopsy-proven ...
Yusuke Kajimoto +7 more
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Glomerular Podocytes and Adhesive Interaction with Glomerular Basement Membrane
Nephron Experimental Nephrology, 1999Normal podocyte function requires attachment to the underlying glomerular basement membrane. Alteration or disruption of podocyte attachment occurs in many forms of glomerular injury, leading to the development of proteinuria and eventually progressive glomerulosclerosis.
P, Mundel, S J, Shankland
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Anti–Glomerular Basement Membrane Glomerulonephritis
New England Journal of Medicine, 2023openaire +2 more sources
Glomerular Basement Membrane in Diabetics
American Journal of Clinical Pathology, 1966P, Kimmelstiel, G, Osawa, J, Beres
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[Thin glomerular basement membrane disease].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2008Thin glomerular basement membrane disease (TBMD) is a hereditary nephropathy characterized by thinning of the glomerular basement membrane evinced by electron microscopy and, clinically, by isolated hematuria without extrarenal manifestations. Familial aggregation is found in 50-60% of cases, with autosomal dominant transmission.
G M, FrascĂ +7 more
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Thickness of Glomerular Basement Membranes
American Journal of Clinical Pathology, 1966G, Osawa, P, Kimmelstiel, V, Seiling
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