Results 211 to 220 of about 36,211 (244)
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Pathology of glomerular basement membrane nephropathy
Current Opinion in Nephrology and Hypertension, 1994Studies of the molecular pathology of glomerular basement membrane have led to the discovery of four novel chains of type IV collagen, the latest of which is the alpha 6(IV) chain. Three chains have been shown to be directly involved in the pathogenesis of Goodpasture syndrome, Alport syndrome, and Alport posttransplantation antiglomerular basement ...
B G, Hudson, R, Kalluri, K, Tryggvason
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Molecular Sieving by Glomerular Basement Membrane
Nature, 1967OF the three layers of the glomerular capillary wall—endothelial cells, basement membrane and epithelial cells—the basement membrane appears to be the only complete barrier between the plasma and the glomerular filtrate1,2. Support for the view that the basement membrane is the most important filtering mechanism was provided by the studies on ferritin ...
F, Huang, L, Hutton, N, Kalant
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2010
The glomerular basement membrane shown in panel A differs from basement membranes in other locations in that it is faced by a cell layer on either side, namely the endothelia and the podocytes and that it is thicker, because it is the product of fusion of the basement membrane of endothelial cells and podocytes.
Margit Pavelka, Jürgen Roth
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The glomerular basement membrane shown in panel A differs from basement membranes in other locations in that it is faced by a cell layer on either side, namely the endothelia and the podocytes and that it is thicker, because it is the product of fusion of the basement membrane of endothelial cells and podocytes.
Margit Pavelka, Jürgen Roth
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Antigens of the human glomerular basement membrane
Springer Seminars in Immunopathology, 1987The intent of the previous discussion has been to acquaint the reader with the recent expanding knowledge in matrix biochemistry and immunopathology as it pertains to the human GBM. However, it must be emphasized that the GBM antigens, which have yet to be characterized, may outnumber those that are currently defined.
L S, Fouser, A F, Michael
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Inherited Diseases of the Glomerular Basement Membrane
American Journal of Kidney Diseases, 1994The inherited diseases of the glomerular basement membrane include Alport's syndrome (AS), nail-patella syndrome, and thin basement membrane nephropathy. Classical AS is inherited in an X-linked manner and accounts for approximately 85% of the cases. Its manifestations include hematuria, sensorineural hearing loss, ocular defects, and a progression to ...
K A, Bodziak +2 more
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Inherited diseases of the glomerular basement membrane
Nature Clinical Practice Nephrology, 2008The glomerular basement membrane (GBM) is a specialized form of basement membrane that has a major role in the maintenance of the glomerular filtration barrier. Like all basement membranes, it contains four main components: type IV collagen, laminin, nidogen, and heparan sulfate proteoglycans.
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The deposition of silver in glomerular basement membrane
Virchows Archiv B Cell Pathology, 1972The sequential deposition of silver in glomerular basement membrane was studied electron microscopically in a series of rats which had ingested 12 mM AgNO3 drinking fluid continually for periods of up to 81 weeks.
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Glomerular Podocytes and Adhesive Interaction with Glomerular Basement Membrane
Nephron Experimental Nephrology, 1999Normal podocyte function requires attachment to the underlying glomerular basement membrane. Alteration or disruption of podocyte attachment occurs in many forms of glomerular injury, leading to the development of proteinuria and eventually progressive glomerulosclerosis.
P, Mundel, S J, Shankland
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VACUOLIZATION OF THE GLOMERULAR BASEMENT MEMBRANE
Acta Pathologica Microbiologica Scandinavica Section A Pathology, 1979Immunofluorescence and clinical data were collected retrospectively and renal tissue was examined by electron microscopy 1) for 20 consecutive patients whose glomeruli were normal in light microscopy except for vacuolization of obliquely‐cut portions of the glomerular basement membrane (GBM) after periodic acid‐silver‐methenamine staining, and 2) for ...
GUSTAV TALLQVIST +3 more
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The glomerular basement membrane in lupus nephritis
Microscopy Research and Technique, 1994AbstractSystemic lupus erythematosus is a disease that is particularly suited for studies of glomerular basement membrane pathology. Classification of the renal pathology of lupus nephritis is usually based on light microscopic features, combined with immunofluorescence findings and electron microscopic alterations.
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