Understanding eGFR Trajectories and Kidney Function Decline via Large Multimodal Models [PDF]
arXivThe estimated Glomerular Filtration Rate (eGFR) is an essential indicator of kidney function in clinical practice. Although traditional equations and Machine Learning (ML) models using clinical and laboratory data can estimate eGFR, accurately predicting future eGFR levels remains a significant challenge for nephrologists and ML researchers.
arxiv
Initial Experience of Metabolic Imaging with Hyperpolarized [1-13C]pyruvate MRI in Kidney Transplant Patients [PDF]
BACKGROUND: Kidney transplant is the treatment of choice for patients with end-stage renal disease. Early detection of allograft injury is important to delay or prevent irreversible damage. PURPOSE: To investigate the feasibility of hyperpolarized (HP) [1-13C]pyruvate MRI for assessing kidney allograft metabolism. SUBJECTS: 6 participants (mean age, 45.
arxiv +1 more source
British Journal of Clinical Pharmacology, EarlyView.Objective To determine the optimal anticoagulation intensity of warfarin in a South‐East Asian population with moderate‐to‐severe rheumatic mitral stenosis. Methods A multicentre, retrospective study examined patients with rheumatic mitral stenosis who had not undergone valve replacement or repair and required long‐term warfarin therapy at two ...
Punyawee Puchsaka +6 more
wiley +1 more source
Editorial: Glomerular filtration rate in Chronic Kidney Disease
Frontiers in Medicine, 2023 Ana Maria Cusumano +2 more
doaj +1 more source
Micropuncture Study of the Effect of Acute Reductions in Glomerular Filtration Rate on Sodium and Water Reabsorption by the Proximal Tubules of the Rat* [PDF]
, 1965 Sheldon Glabman +2 more
openalex +1 more source
Med-gte-hybrid: A contextual embedding transformer model for extracting actionable information from clinical texts [PDF]
arXivWe introduce a novel contextual embedding model med-gte-hybrid that was derived from the gte-large sentence transformer to extract information from unstructured clinical narratives. Our model tuning strategy for med-gte-hybrid combines contrastive learning and a denoising autoencoder.
arxiv
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen +9 more
wiley +1 more source
Influence of Expansion of Extracellular Volume on Tubular Reabsorption of Sodium Independent of Changes in Glomerular Filtration Rate and Aldosterone Activity * [PDF]
, 1964 Floyd C. Rector +3 more
openalex +1 more source
Algorithmic Changes Are Not Enough: Evaluating the Removal of Race Adjustment from the eGFR Equation [PDF]
arXivChanging clinical algorithms to remove race adjustment has been proposed and implemented for multiple health conditions. Removing race adjustment from estimated glomerular filtration rate (eGFR) equations may reduce disparities in chronic kidney disease (CKD), but has not been studied in clinical practice after implementation. Here, we assessed whether
arxiv
PurposeUrological disorders are the most common cause of pediatric chronic kidney disease. We determined the characteristics of children with urological disorders and assessed the agreement between the newly developed bedside glomerular filtration rate ...
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