Results 171 to 180 of about 419,925 (401)
GLOMERULAR FILTRATION RATE IN SICK ELDERLY INPATIENTS [PDF]
M.J. Denham, H. M. HODKINSON, M. Fisher
openalex +1 more source
Objective Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes, and decreased nephrin production.
Rhea Bhargava+9 more
wiley +1 more source
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to 3 years; all patients received mycophenolate mofetil and low‐dose glucocorticoids.
Brad H. Rovin+9 more
wiley +1 more source
Objective The presence of antinuclear antibodies (ANAs) is characteristic for systemic lupus erythematosus (SLE). Antibody dynamics over time are thought to reflect the cellular source of ANAs and their therapeutic targetability. Anti–double‐stranded DNA (anti‐dsDNA) is the most prevalent and well‐studied of all ANAs, and fluctuations in anti‐dsDNA ...
Hugo J. van Dooren+16 more
wiley +1 more source
1052 GLOMERULAR FILTRATION RATE(GFR) IN CHILDREN WITH VESICO-URETHRAL(V-U) REFLUX: Cr51 CLEARANCE(C) VERSUS INULIN AND ENDOGENOUS CREATININE CLEARANCE (ECC) [PDF]
Yoram Blachar+4 more
openalex +1 more source
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun+19 more
wiley +1 more source
Background: Contrast-induced nephropathy is a prevalent cause of hospital-acquired renal insufficiency and increases adverse events in older patients undergoing angiography and percutaneous coronary intervention.
Tan Van Nguyen+4 more
doaj +1 more source
Management of Proteinuria in Dogs and Cats with Chronic Kidney Disease [PDF]
Atkins+46 more
core +1 more source