Results 171 to 180 of about 435,208 (390)

Allogeneic bone marrow-derived mesenchymal stem cells in the aging kidney: secondary results of a Parkinson’s disease clinical trial

Stem Cell Research & Therapy
Background Kidney function declines with age, largely due to chronic low-grade inflammation. Mesenchymal stem cells (MSCs) have demonstrated immunomodulatory effects in certain immune-mediated kidney diseases, but their role in preserving renal function ...
Juan D. Martinez-Lemus, Donald A. Molony, Jessika Suescun, Emily Tharp, Tia S. Thomas, Charles Green, Chiamaka Onuigbo, Robert Ritter, Mya C. Schiess   +8 more
doaj   +1 more source

Evaluation of Renal Function in Obese Children and Adolescents Using Serum Cystatin C Levels, Estimated Glomerular Filtration Rate Formulae and Proteinuria: Which is most Useful?

, 2019
Dilşah Önerli Salman, Zeynep Şıklar, Nisa Eda Çullas İlarslan, Zeynep Birsin Özçakar, Pınar Kocaay, Merih Berberoğlu   +5 more
openalex   +1 more source

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis

The Lancet, 2010
K. Matsushita, Marije van der Velde, B. Astor, M. Woodward, A. Levey, P. D. de Jong, J. Coresh, R. Gansevoort   +7 more
semanticscholar   +1 more source

Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature

British Journal of Clinical Pharmacology, EarlyView.
Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen, Daan J. Touw, Kim Klein, Gertjan J. L. Kaspers, Paola Mian   +4 more
wiley   +1 more source

Association between eGFR and neurological outcomes among patients with out‐of‐hospital cardiac arrest: A nationwide prospective study in Japan

Acute Medicine & Surgery
Aim We aimed to investigate the association between estimated glomerular filtration rate and prognosis in out‐of‐hospital cardiac arrest patients and explore the heterogeneity of the association.
Kenji Kandori, Asami Okada, Satoshi Nakajima, Tasuku Matsuyama, Tetsuhisa Kitamura, Hiromichi Narumiya, Ryoji Iizuka, Masahito Hitosugi, Yohei Okada   +8 more
doaj   +1 more source

Estimation of Glomerular Filtration Rate to Adjust Vancomycin Dosage in Critically Ill Patients: Superiority of the Chronic Kidney Disease Epidemiology Collaboration Equation? [PDF]

, 2014
Jean‐Marie Conil, B. Georges, Audrey Breden, Stéphanie Ruiz, P. Cougot, Olivier Fourcade, Sylvie Saivin   +6 more
openalex   +1 more source

Safety and pharmacokinetics of a novel potent GABA analogue crisugabalin in Chinese subjects with various degrees of renal impairment

British Journal of Clinical Pharmacology, EarlyView.
Aims Crisugabalin is a novel calcium channel α2δ subunit ligand and a highly selective oral gamma‐aminobutyric acid (GABA) analogue developed for the treatment of diabetic peripheral neuropathic pain (DPNP) and postherpetic neuralgia (PHN). This study investigated pharmacokinetic properties and safety of crisugabalin in subjects with renal impairment ...
Shibeilei Lin, Ye Wang, Chao Hu, Yanhuan Feng, Xi Tang, Ping Fu, Jia Miao   +6 more
wiley   +1 more source

Dynamic changes in the real-time glomerular filtration rate and kidney injury markers in different acute kidney injury models

Journal of Translational Medicine
In this study, we dynamically monitored the glomerular filtration rate and other assessment of renal function and markers of injury in various mice models of acute kidney injury.
Yu Xin, Yanqi Liu, Linqiong Liu, Xinran Wang, Dawei Wang, Yuchen Song, Lifeng Shen, Yuxi Liu, Yuhan Liu, Yahui Peng, Xibo Wang, Yang Zhou, Hongxu Li, Yuxin Zhou, Pengfei Huang, Mengyao Yuan, Yu Xiao, Kaijiang Yu, Changsong Wang   +18 more
doaj   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Human vs. artificial intelligence: Physicians outperform ChatGPT in real‐world pharmacotherapy counselling

British Journal of Clinical Pharmacology, EarlyView.
Aims To assess the utility of the artificial intelligence (AI) chatbot ChatGPT (openly available version 3.5) in responding to real‐world pharmacotherapeutic queries from healthcare professionals. Methods Three independent and blinded evaluators with different levels of medical expertise and professional experience (beginner, advanced, and expert ...
Benjamin Krichevsky, Stefan Engeli, Stefanie M. Bode‐Böger, Felix Koop, Martin Schulze Westhoff, Sebastian Schröder, Carsten Schumacher, Thorben Pape, Dirk O. Stichtenoth, Johannes Heck   +9 more
wiley   +1 more source