Results 171 to 180 of about 325,932 (347)

Estimating Glomerular Filtration Rate in Young Persons With Obesity or Diabetes and Hyperfiltration. [PDF]

open access: yesKidney Int Rep
Bekelman NJ   +7 more
europepmc   +1 more source

Cystatin C‐based eGFR better predicts renal vancomycin clearance than creatinine‐based eGFR in patients with allogeneic stem cell transplantation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Knowledge of the glomerular filtration rate (GFR) is mandatory when dosing renally eliminated drugs such as vancomycin. In clinical practice, different biomarkers and various equations are used to estimate GFR (eGFR), resulting in varying estimates.
Eva‐Maria A. Wansing   +7 more
wiley   +1 more source

SAT-080 ESTIMATED GLOMERULAR FILTRATION RATE TRAJECTORIES TWO YEARS PRIOR TO DIALYSIS INITIATION IN CAMEROON

open access: gold, 2020
H. Fouda   +5 more
openalex   +1 more source

Biomarkers of Drug‐Induced Kidney Injury: Use in Clinical Trials and Recent Examples of Impact on Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
This manuscript describes the scope of implementation and impact of a regulatory agency‐qualified panel of six urine biomarkers on drug development, the process for which was conducted and funded by the Critical Path Institute, the Foundation for the National Institutes of Health, and the United States Food and Drug Administration.
Tanja S. Zabka   +7 more
wiley   +1 more source

Contribution of the glomerular filtration rate slope to the kidney hierarchical composite endpoint

open access: hybrid
Dustin J. Little   +5 more
openalex   +1 more source

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park   +22 more
wiley   +1 more source

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