Postnatal maturation of the glomerular filtration rate in conventional growing piglets as potential juvenile animal model for preclinical pharmaceutical research [PDF]
, 2017 Adequate animal models are required to study the preclinical pharmacokinetics (PK), pharmacodynamics (PD) and safety of drugs in the pediatric subpopulation.
Croubels, Siska +8 more
core +3 more sources
Obesity and glomerular filtration rate
International Urology and Nephrology, 2023 Obesity has received considerable attention in general medicine and nephrology over the last few years. This condition increases the risk of metabolic syndrome, diabetes mellitus, hypertension, and dyslipidemia, which are the main risk factors for developing chronic kidney disease (CKD).
Paula Schwartz +5 more
openaire +3 more sources
BMC Cancer, 2020 Background Formulae of estimated glomerular filtration rate (eGFR) based on serum creatinine (Scr) are routinely used in oncology patients, however, they are inaccurate in some populations. Our aim was to assess the agreement of eGFR formulae and thereby
Yichun Cheng +5 more
doaj +1 more source
Acta Dermato-Venereologica, 2022 While dialysis is linked with prurigo nodularis, little is known about the impact of non-dialysis chronic kidney disease on prurigo nodularis. The influence of chronic kidney disease on development of prurigo nodularis was measured using the Korean ...
Hei Sung Kim +2 more
doaj +1 more source
Use of Estimating Equations for Dosing Antimicrobials in Patients with Acute Kidney Injury Not Receiving Renal Replacement Therapy. [PDF]
, 2018 Acute kidney injury (AKI) can potentially lead to the accumulation of antimicrobial drugs with significant renal clearance. Drug dosing adjustments are commonly made using the Cockcroft-Gault estimate of creatinine clearance (CLcr). The Modified Jelliffe
Awdishu, Linda +5 more
core +2 more sources
Comparing Results of Five Glomerular Filtration Rate-Estimating Equations in the Korean General Population. MDRD Study, Revised Lund-Malmö, and Three CKD-EPI Equations [PDF]
, 2016 Estimated glomerular filtration rate (eGFR) is a widely used index of kidney function. Recently, new formulas such as the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations or the Lund-Malmö equation were introduced for assessing eGFR.
Han-Ik Cho +8 more
core +1 more source
Post-kidney donation glomerular filtration rate measurement and estimation
Nefrología (English Edition), 2021 Background: Long-term consequences associated with kidney donation are controversial. Pre- and post-donation glomerular filtration rates (GFRs) are determinants of renal and cardiovascular risk weighting.
Pablo Luján +5 more
doaj +1 more source
Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]
, 2018 Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco +6 more
core +1 more source
Neural Network-Based Calculator for Rat Glomerular Filtration Rate
Biomedicines, 2022 Glomerular filtration is a pivotal process of renal physiology, and its alterations are a central pathological event in acute kidney injury and chronic kidney disease.
Óscar J. Pellicer-Valero +8 more
doaj +1 more source
Efectos de la circulación extracorpórea sobre el filtrado glomerular en la cirugía cardiovascular pediátrica [PDF]
, 2009 Objetivoconocer como afecta la circulación extracorpórea la función renal tomando como marcador la alteración del filtrado glomerular.Material y métodose realizó un estudio prospectivo, analítico y observacional en 63 pacientes pediátricos sometidos a ...
Devarajan +21 more
core +2 more sources