Results 41 to 50 of about 353,912 (198)

Single-Nephron Glomerular Filtration Rate in Healthy Adults

New England Journal of Medicine, 2017
BACKGROUND The glomerular filtration rate (GFR) assesses the function of all nephrons, and the single‐nephron GFR assesses the function of individual nephrons.
Aleksandar Denic, J. Mathew, L. Lerman, J. Lieske, J. Larson, M. Alexander, E. Poggio, R. Glassock, A. Rule   +8 more
semanticscholar   +2 more sources

Hyperuricemia and Impaired Renal Function: A Prospective Cohort Study

Kidney Diseases, 2020
Background: Related studies have demonstrated a relationship of elevated serum uric levels with a decline in kidney function. However, limited evidence exists in a Southeast Asian community-based population.
Noppawit Aiumtrakul, Puvanant Wiputhanuphongs, Ouppatham Supasyndh, Bancha Satirapoj   +3 more
doaj   +1 more source

Comparison of Creatinine, Cystatin C and Combined Creatinine-Cystatin C for Renal Function Assessment in Patients with Diabetes

Pakistan Armed Forces Medical Journal, 2022
Objective: To compare the estimated glomerular filtration rate (eGFR) assessed through the CKD-EPI equations based on creatinine, Cystatin C and creatinine-Cystatin C levels for estimating kidney function among patients with diabetes.
Saba Umar, Sohail Sabir, Nadeem Malik Azam, Muhaamad Aamir, Afshan Bibi, Ashfaq Altaf, Faud Ahmed Siddiqui, Haroon Sabir, Khalid Mehmood Raja, Batool Butt   +9 more
doaj   +1 more source

Renal function: Estimation of glomerular filtration rate [PDF]

Journal of Medical Biochemistry, 2007
The glomerular filtration rate (GFR) is widely accepted as the best overall measure of kidney function. American National Kidney Foundation guidelines define chronic kidney disease (CKD) by either a GFR of less than 60 mL/min/1.73 m2 or the presence of ...
Dajak Marijana, Ignjatović Svetlana, Majkić-Singh Nada   +2 more
doaj  

Measurement and Estimation of Glomerular Filtration Rate in Children

Advances in Chronic Kidney Disease, 2017
Rapid, accurate, and precise measures of kidney function are essential for the daily management of patients. While plasma and urinary clearances provide the greatest accuracy for assessing glomerular filtration rate (GFR), they are often impractical ...
Ayesa N. Mian, G. Schwartz
semanticscholar   +1 more source

Application of the formula for estimating glomerular filtration rate in the elderly population

Linchuang shenzangbing zazhi
ObjectiveTo accurately assess the importance of glomerular filtration rate in the elderly population， explore the clinical characteristics of the elderly population who need to monitor glomerular filtration rate， and verify the performance of the ...
Yang Dan, Ge Shu-wang, Xu Gang
doaj   +3 more sources

Abemaciclib inhibits renal tubular secretion without changing glomerular filtration rate

Clinical pharmacology and therapy, 2018
Abemaciclib, an inhibitor of cyclin dependent kinases 4 and 6, is indicated for metastatic breast cancer treatment. Reversible increases in serum creatinine levels of ~15–40% over baseline have been observed following abemaciclib dosing.
J. Chappell, P. Turner, Y. A. Pak, J. Bacon, A. Chiang, J. Royalty, Stephen D. Hall, P. Kulanthaivel, J. Bonventre   +8 more
semanticscholar   +1 more source

The intrinsic circadian clock in podocytes controls glomerular filtration rate

Scientific Reports, 2019
Glomerular filtration rate (GFR), or the rate of primary urine formation, is the key indicator of renal function. Studies have demonstrated that GFR exhibits significant circadian rhythmicity and, that these rhythms are disrupted in a number of ...
Camille Ansermet, G. Centeno, S. Nikolaeva, M. Maillard, S. Pradervand, D. Firsov   +5 more
semanticscholar   +1 more source

Glomerular Filtration Rate [PDF]

JAMA, 1967
Martin S. Knapp, W. H. C. Walker
  +7 more sources

Evaluation of Biomarker-Based Glomerular Filtration Rate Estimating Equations in Glomerular Disease

Glomerular Diseases
Introduction: Glomerular filtration rate (GFR) is typically estimated with equations that use biomarkers such as serum creatinine and/or cystatin-C. The impact of these different biomarkers on GFR estimates in glomerular disease patients is unclear.
Antara Mondal, Christina Kobe, Laura H. Mariani, Jarcy Zee   +3 more
doaj   +1 more source