Results 51 to 60 of about 240,527 (296)

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Incomplete reversibility of eGFR following tenofovir exposure [PDF]

, 2014
Background. Tenofovir disoproxil fumarate (TDF) has been linked to renal impairment but the extent to which this impairment is reversible is unclear. We aimed to investigate the reversibility of renal decline on TDF.Methods.
Lisa Hamzah, Richard Gilson, Lucy J. Campbell, John Walsh, Jones, R, Chadwick, D, Frank A. Post, Post, FA, Leen, Clifford, Sophie Jose, Hill, Teresa, Campbell, Lucy J, Jose, Sophie, Campbell, Lucy J., Nitsch, D, Sabin, Caroline, Sabin, Caroline A, Dorothea Nitsch, Rachael Jones, UK Collaborative HIV Cohort Study Steering Committee, Campbell, LJ, Hay, Phillip, Johnson, M, Martin Fisher, Sabin, Caroline A., Gilson, Richard, Fisher, M, ?, ?, Johnson, Margaret, Post, Frank A, Gilson, R, Hay, P, Post, Frank A., Caroline A. Sabin, Phillip Hay, Nelson, Mark, Teresa Hill, Hamzah, L, Mark Nelson, Fisher, Martin, Walsh, J, Hill, T, Chadwick, David, Hamzah, Lisa, Margaret Johnson, David Chadwick, Sabin, CA, Walsh, John, Nelson, M, Jones, Rachael, Clifford Leen, Campbell, Lucy, Post, Frank, Jose, S, Nitsch, Dorothea, Leen, C   +55 more
core   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Evaluation of Biomarker-Based Glomerular Filtration Rate Estimating Equations in Glomerular Disease

Glomerular Diseases
Introduction: Glomerular filtration rate (GFR) is typically estimated with equations that use biomarkers such as serum creatinine and/or cystatin-C. The impact of these different biomarkers on GFR estimates in glomerular disease patients is unclear.
Antara Mondal, Christina Kobe, Laura H. Mariani, Jarcy Zee   +3 more
doaj   +1 more source

Limited value of cystatin-C over estimated glomerular filtration rate for heart failure risk stratification. [PDF]

PLoS ONE, 2012
BackgroundTo compare the prognostic value of estimated glomerular filtration rate, cystatin-C, an alternative renal biomarker, and their combination, in an outpatient population with heart failure.
Elisabet Zamora, Josep Lupón, Josep Lupón, Marta de Antonio, Joan Vila, Amparo Galán, Paloma Gastelurrutia, Agustín Urrutia, Antoni Bayes-Genis   +8 more
doaj   +1 more source

Fluid balance, glomerular filtration rate, and urine output in dogs anesthetized for an orthopedic surgical procedure

, 2010
OBJECTIVE: To determine fluid retention, glomerular filtration rate, and urine output in dogs anesthetized for a surgical orthopedic procedure. ANIMALS: 23 dogs treated with a tibial plateau leveling osteotomy.
Francey, T., Dowers, K., Siao, K.T., Pypendop, B.H., Boscan, P., Cowgill, L., Ilkiw, J.E.   +6 more
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Creatinine clearance versus serum creatinine as a risk factor in cardiac surgery

, 2003
Walter JA, Mortasawi A, Arnrich B, et al. Creatinine clearance versus serum creatinine as a risk factor in cardiac surgery. BMC Surgery. 2003;3(1): 4.BACKGROUND: Renal impairment is one of the predictors of mortality in cardiac surgery.
Mortasawi, Amir, Inez Frerichs, Albert, Alexander, Mortasawi Amir, Rosendahl Ulrich, Frerichs, Inez, Alexander Albert, Ulrich Rosendahl, Jürgen Ennker, Amir Mortasawi, Walter, Jörg, Arnrich, Bert, Rosendahl, Ulrich, Frerichs Inez, Albert Alexander, Arnrich Bert, Ennker Jürgen, Jörg Walter, Bert Arnrich, Walter, Jörg A., Walter Jörg, Ennker, Jürgen   +21 more
core   +1 more source

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source