Results 61 to 70 of about 240,527 (296)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Ultrasound characteristics and correlation with estimated glomerular filtration rate in patients with chronic kidney disease: A facility-based cross-sectional study

open access: yesJournal of International Medical Research
Objective To evaluate grayscale sonographic characteristics and their correlation with the estimated glomerular filtration rate. Methodology: This cross-sectional study included 103 patients with stage III and above chronic kidney disease.
Fekadu H Getaneh   +3 more
doaj   +1 more source

Glomerular filtration rate and initiation of dialysis [PDF]

open access: yesCanadian Medical Association Journal, 2010
In this issue, Clark and colleagues[1][1] present data showing a relationship between higher estimated glomerular filtration rate at the start of hemodialysis and mortality. Their results confirm the findings of previous observational studies.
Stel, Vianda S., Jager, Kitty J.
openaire   +3 more sources

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

open access: yesAdvanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler   +4 more
wiley   +1 more source

Glomerular filtration rate.

open access: yes, 2019
Glomerular filtration rate at baseline and following ischemia reperfusion after CA inhibition (n = 11) and corresponding vehicle treatment (n = 12).
Oskar Nensén (7325957)   +2 more
core   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang   +9 more
wiley   +1 more source

Impairment in Glomerular Filtration Rate or Glomerular Filtration Barrier and Occurrence of Stroke [PDF]

open access: yesArchives of Neurology, 2008
Chronic kidney disease (CKD) is associated with substantial burden and is a strong risk factor for cardiovascular disease. However, data on the relationship between CKD and stroke are few and are limited by unreliable or inadequate assessment of renal function.To properly assess the relationship between renal insufficiency and stroke in stroke ...
openaire   +2 more sources

A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells

open access: yesAdvanced Science, EarlyView.
A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong   +13 more
wiley   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

open access: yesAdvanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du   +15 more
wiley   +1 more source

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