Results 41 to 50 of about 8,265 (168)
Compartment‐Specific Immune Remodeling of Renal Aging With C1q‐Associated Podocyte Activation
The FASEB Journal, Volume 40, Issue 11, 15 June 2026.Aging repatterns the renal immune response in a compartment‐specific manner, distinct from chronic kidney disease (CKD) adaptation. Glomerular aging features C1q‐associated podocyte activation and macrophage engagement, whereas tubulointerstitial aging is marked by B‐cell aggregation and tertiary lymphoid structure expansion.
Ju‐Young Moon +10 more
wiley +1 more source
BMC Nephrology, 2012 Background Subacute bacterial endocarditis (SBE) occasionally exhibits positive cytoplasmic anti-neutrophil cytoplasmic antibody (c-ANCA) of the anti-proteinase-3 (PR-3) type.
Peng Hui +6 more
doaj +1 more source
Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles
European Journal of Immunology, Volume 56, Issue 6, June 2026.Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes +2 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2011 Distinct patterns of glomerular lesions, including membranoproliferative glomerulonephritis and focal segmental glomerulosclerosis, are associated with infection by Schistosoma mansoni or Schistosoma japonicum.
Washington Luis Conrado dos-Santos +3 more
doaj +1 more source
Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background Diabetic nephropathy is among the most critical long‐term complications linked to diabetes, substantially influencing both morbidity and mortality. Although it was once largely associated with adults, diabetic kidney disease (DKD) has now become a leading source of kidney complications among children worldwide.
Iran Malekzadeh +6 more
wiley +1 more source
The Pan African Medical Journal, 2021 INTRODUCTION: Membranoproliferative glomerulonephritis (MPGN) is a rare kidney disease with a poor prognosis as 50% of patients attend the end stage renal failure after 10 years of follow up. Several factors have been described associated with poor renal
Ikram Agrebi +6 more
doaj +1 more source
Secondary membranoproliferative glomerulonephritis
Kidney International, 1995 A 37-year-old man was transferred to Brigham and Women's Hospital for evaluation of progressive renal failure. His medical history was notable for intravenous drug use and heavy ethanol consumption but he denied their use for the last 7 years. He had had at least one bout of alcoholic hepatitis, which was diagnosed about 8 years previously. The patient
openaire +2 more sources
British Journal of Pharmacology, Volume 183, Issue 11, Page 2874-2889, June 2026.Abstract Background and Purpose Overactivation of the alternative pathway (AP) underlies several diseases. Iptacopan is an oral, first‐in‐class, highly potent specific inhibitor of factor B, a key AP protease. Experimental Approach The analysis included data from two phase 1 randomised, volunteer‐blinded, placebo‐controlled studies: Study 1, a single ...
Irina Baltcheva +5 more
wiley +1 more source
Cardiac Angiosarcoma-Associated Membranoproliferative Glomerulonephropathy
Case Reports in Medicine, 2011 Primary cardiac angiosarcoma is a rare cardiac tumor. The initial clinical course is often asymptomatic, and metastatic disease is present in a majority of affected patients at diagnosis.
Lokesh Shahani +2 more
doaj +1 more source
Membranoproliferative Glomerulonephritis Associated with Nivolumab Therapy
Case Reports in Nephrology, 2020 Nivolumab is an immune checkpoint inhibitor that targets programmed death-1 on T cells and is designed to amplify an immunologic reaction against cancer cells.
Jessica Cruz-Whitley +3 more
doaj +1 more source