Results 41 to 50 of about 11,966 (187)

Targeting the miR‐224‐5p/PTEN pathway: A previously under‐characterized strategy to attenuate mesangial cell injury and predict prognosis in diabetic nephropathy

Journal of Diabetes Investigation, EarlyView.
Serum miR‐224‐5p levels are progressively elevated in diabetic nephropathy (DN) and serve as an independent predictor of a decline in eGFR of ≥30% over 2 years. Mechanistically, miR‐224‐5p directly targets PTEN 3’‐UTR, suppressing PTEN and the activation of the AKT pathway in high‐glucose‐stimulated mesangial cells.
Yanxia Gao, Xiaohui Zhang, Peng Lu, Qiang Wang   +3 more
wiley   +1 more source

Neonatal Acute Kidney Injury—An Australian and New Zealand Perspective

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Acute kidney injury (AKI) is increasingly recognized as a critical and underdiagnosed condition among neonates, with significant short and long‐term implications for survival, kidney function, and long‐term cardiovascular health. Neonatal physiology, including ongoing nephrogenesis, immature renal haemodynamics, and limited glomerular ...
Saumil Desai, Thomas Forbes, Simon A. Carter, Alison L. Kent, Chanel Prestidge, David T. Selewski, Eveline Staub, Anke Raaijmakers   +7 more
wiley   +1 more source

Can influenza H1N1 vaccination lead to the membranous glomerulonephritis?

Indian Journal of Pathology and Microbiology, 2012
In 2009 winter, Influenza A (H1N1) monovalent split virus vaccine was used prevalently in the whole world as a result of the pandemic caused by Influenza (H1N1) virus.
Ali Kutlucan, Ibak Gonen, Esra Yildizhan, Yusuf Aydin, Tansu Sav, Umran Yildirim   +5 more
doaj   +1 more source

Anti-phospholipase A2 Receptor Antibody-Positive Membranous Glomerulopathy due to Anti-Koch’s Therapy in a Tuberculosis Patient

Saudi Journal of Kidney Diseases and Transplantation, 2021
Tuberculosis (TB)-associated glomerulonephritis is difficult to diagnose that usually presents with hematuria, proteinuria, edema, hypertension, or renal insufficiency, which is similar to symptoms of primary glomerulonephritis.
Manish R. Balwani, Amit S. Pasari, Amol Bhawane, Priyanka Tolani   +3 more
doaj   +1 more source

Clinical implications of imlifidase interference in antibody screening and transfusion management

Transfusion, EarlyView.
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani, Aiko P. J. de Vries, Arjan Albersen   +2 more
wiley   +1 more source

RENAL HISTOPATHOLOGICAL FINDINGS IN DOGS WITH VISCERAL LEISHMANIASIS

Revista do Instituto de Medicina Tropical de São Paulo, 2013
Visceral leishmaniasis affects various organs including the kidneys; which can lead to renal failure and death. In order to verify this renal involvement, material was evaluated from 100 dogs naturally infected and with serological diagnosis of canine ...
Rosangela Silva Rigo, Cristiano Marcelo Espínola Carvalho, Michael Robin Honer, Gisele Braziliano de Andrade, Iandara Shetter Silva, Leonardo Rigo, Helen Rezende Figueiredo, Wanessa Teixeira Gomes Barreto   +7 more
doaj   +1 more source

Glomerular galactose-deficient IgA1 expression analysis in pediatric patients with glomerular diseases

Scientific Reports, 2020
Galactose-deficient IgA1 (Gd-IgA1) is important in the pathogenesis of IgA nephropathy (IgAN). A Gd-IgA1-specific monoclonal antibody (KM55) has revealed glomerular Gd-IgA1 deposition solely in patients with IgAN and IgA vasculitis with nephritis (IgAV-N)
Shinya Ishiko, Tomoko Horinouchi, Rika Fujimaru, Yuko Shima, Hiroshi Kaito, Ryojiro Tanaka, Shingo Ishimori, Atsushi Kondo, Sadayuki Nagai, Yuya Aoto, Nana Sakakibara, China Nagano, Tomohiko Yamamura, Momoka Yoshimura, Koichi Nakanishi, Junya Fujimura, Naohiro Kamiyoshi, Hiroaki Nagase, Norishige Yoshikawa, Kazumoto Iijima, Kandai Nozu   +20 more
doaj   +1 more source

Mesangial cells in membranous glomerulonephritis [PDF]

Journal of Clinical Pathology, 1973
Renal biopsies of seven patients with membranous glomerulonephritis were examined by light, electron, and immunofluorescence microscopy. All had characteristic changes of glomerular basement membranes, typically with bright granular membranous fluorescence of IgG and variable deposits of complement.
P A, Portch, G, Williams
openaire   +2 more sources

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Trends in Clinical Indications for Plasma Exchange in Adult Patients Between 2008 and 2024 in Bogotá, Colombia

Journal of Clinical Apheresis, Volume 41, Issue 4, August 2026.
ABSTRACT This multicenter retrospective study aimed to describe temporal trends in clinical indications for plasma exchange (PE) in adult patients at four quaternary‐care hospitals in Bogotá (2008–2024) and to examine their distribution across successive ASFA guideline editions.
Edgar Julián Reyes, Federico Tovar‐Avendaño, Camilo Alberto Gonzalez‐Gonzalez, Diana Carolina Vargas‐Angel, Jorge Pulido, Paula Violeta Rodríguez, Deiner‐Yivelson Muñoz‐Delgado, Kateir Contreras‐Villamizar   +7 more
wiley   +1 more source