Results 81 to 90 of about 13,324 (216)
Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease
This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley +1 more source
Focal glomerulosclerosis in idiopathic membranous glomerulonephritis
Focal glomerulosclerosis in idiopathic membranous glomerulonephritis. The significance of the finding of focal glomerulosclerosis (FGS) in idiopathic membranous glomerulonephritis (MGN) is uncertain. Twenty-seven patients with mixed FGS and MGN (MGN-FGS)
Wakai, Sachiko, Magil, Alex B.
core +1 more source
The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley +1 more source
A transition from proliferative to membranous glomerulonephritis in chronic serum sickness
Transition of proliferative to membranous glomerulonephritis in chronic serum sickness. Chronic serum sickness glomerulonephritis was induced in rats by daily i.v. administration of bovine serum albumin (BSA). Previous studies have shown that the disease
Van Liew, Judith B. +2 more
core +1 more source
ABSTRACT Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a form of monoclonal gammopathy of renal significance (MGRS) in which monoclonal immunoglobulin deposits are found within the glomerulus, without involvement of other renal compartments.
Hayley J. Duxbury +5 more
wiley +1 more source
ObjectiveTo explore the distribution characteristics and disease spectrum changes of pathological types in patients with renal puncture biopsy.MethodsFrom January,2005 to December,2019,clinicopathological data were retrospectively reviewed for 1703 renal
Huang Chun-lin +7 more
doaj
Changes in the diagnosis of glomerular diseases in east China: a 15-year renal biopsy study
Background: There have been some gradual changes in the distribution of renal biopsy pathological diagnoses during recent years. This study aimed to show changes in renal disease prevalence in China by investigating 10 patients diagnosed at our Kidney ...
Qin Zhou +12 more
doaj +1 more source
Inhibition of the CD40-CD40ligand pathway prevents murine membranous glomerulonephritis
Inhibition of the CD40-CD40ligand pathway prevents murine membranous glomerulonephritis. Several forms of glomerulonephritis are induced by antibodies against self or foreign antigens. Normal B lymphocyte antibody production requires T cell costimulatory
Biancone, L. +9 more
core +1 more source
Hepatitis-B-associated glomerulonephritis in children
Three cases with hepatitis B virus (HBV)-related, biopsy-diagnosed glomerulopathies, one of which was membranous glomerulonephritis and the others membranoproliferative glomerulonephritis, are reported, emphasizing the clinical course.
A Oner, K Tinaztepe, G Demircin
doaj

