Results 111 to 120 of about 175,446 (337)

GNS561 (ezurpimtrostat), a small basic lipophilic molecule, prevents lupus phenotype in a pristane‐induced lupus mouse model

British Journal of Pharmacology, EarlyView.
Background and Purpose Systemic lupus erythematosus is an autoimmune, multisystemic disease affecting all organs in the body. Accrued evidence has elucidated a role for autophagy in the onset and severity of systemic lupus erythematosus. The antimalarial drug hydroxychloroquine constitutes the cornerstone of standard of care for systemic lupus ...
Eya Toumi, Eloïne Bestion, Muriel Militello, Hubert Lepidi, Anne Plauzolles, Nathalie Bardin, Daniel Bertin, Laurent Chiche, Jean‐Louis Mege, Philippe Halfon, Soraya Mezouar   +10 more
wiley   +1 more source

Resumption of Meiotic Maturation of Oocytes, Pre- and Post-Implantational Embryonic Mortality under Conditions of Experimental Glomerulonephritis and Treatment of Silver Nanoparticles

Nano Biomedicine and Engineering, 2018
The aim of the current study was to estimate the resumption of meiotic maturation of oocytes, pre- and post-implantation mortality of embryos under conditions of experimental glomerulonephritis and intravenous treatment of silver nanoparticles in mice ...
Taras Viroslavovich Blashkiv, Maria Sergeeevna Stupchuk, Valentine Aleksandrovna Sribna, Oksana Mykolajivna Kalesnykova, Nataliya Georgejivna Grushka, Tetyana Yurievna Voznesenska   +5 more
doaj   +1 more source

Eculizumab for dense deposit disease and C3 glomerulonephritis.

American Society of Nephrology. Clinical Journal, 2012
BACKGROUND AND OBJECTIVES The principle defect in dense deposit disease and C3 glomerulonephritis is hyperactivity of the alternative complement pathway.
A. Bomback, Richard J. H. Smith, G. Barile, Yuzhou Zhang, Eliot C Heher, L. Herlitz, M. Stokes, G. Markowitz, V. D’Agati, P. Canetta, J. Radhakrishnan, G. Appel   +11 more
semanticscholar   +1 more source

Antibiotics for sore throat [PDF]

, 2006
BACKGROUND: Sore throat is a very common reason for people to present for medical care. Although it remits spontaneously, primary care doctors commonly prescribe antibiotics for it.
Barwitz, Bass, Bennike, Bishop, Brink, Brumfitt, Catanzaro, Catanzaro, Chamovitz, Chapple, Cruickshank, Dagnelie, Denny, Denny, Dowell, Driel, El-Daher, Froom, Gerber, Gerber, Ginsburg, Goslings, Guthrie, Haverkorn, Herz, Horder, Howe, Howie, Howie, Howie, Howie, Jensen, Keith, Krober, Landsman, Leelarasamee, Lefebvre, Little, Little, MacDonald, Mar, Mar, Mar, Mar, Mar, Mar, Mar, Marlow, Massell, McDonald, Merenstein, Meyere, Middleton, Morris, Nasonova, Nelson, Pandraud, Peterson, Pichichero, Randolph, Reveiz, Sanders, Schalen, Schalen, Schwartz, Shevrygin, Shvartzman, Siegel, Spinks, Stillerman, Stromberg, Taylor, Todd, Valkenburg, Wannamaker, Wessels, Whitfield, Zwart, Zwart   +78 more
core   +1 more source

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

The Journal of Dermatology, EarlyView.
Yoshihide Asano, Jun Asai, Takayuki Ishii, Yohei Iwata, Masanari Kodera, Chie Miyabe, Akihiko Uchiyama, Youichi Ogawa, Ken Okamura, Mari Kishibe, Yuta Koike, Yorihisa Kotobuki, Noriki Fujimoto, Takuya Miyagi, Yukie Yamaguchi, Ayumi Yoshizaki, Reiko Omori, Takeshi Nakanishi, Hiroshi Fujiwara, Takeo Maekawa, Sei‐ichiro Motegi, Yuichiro Yoshino, Minoru Hasegawa, Manabu Fujimoto, Takao Tachibana, Wound, Pressure Ulcer, and Burn Guidelines Drafting Committee (connective tissue disease/vasculitis group)   +27 more
wiley   +1 more source

Inhibition of Alkbh5 Attenuates Lipopolysaccharide‐Induced Lung Injury by Promoting Ccl1 m6A and Treg Recruitment

Cell Proliferation, EarlyView.
In septic lung injury mice, Alkbh5 is highly expressed, promoting the demethylation of m6A on Ccl1 mRNA, thereby reducing the stability of Ccl1 mRNA and decreasing Ccl1 expression. This, in turn, leads to reduced recruitment of Tregs, further exacerbating the symptoms of septic lung injury.
Hongdou Ding, Xinnan Xu, Yaoyao Zhu, Xinyu Ling, Li Xu   +4 more
wiley   +1 more source

Questions about Chemokine and Chemokine Receptor Antagonism in Renal Inflammation [PDF]

, 2010
Chemokines remain attractive therapeutic targets for modulating inflammatory diseases in all areas of medicine including acute and chronic kidney disease.
Anders, Hans-Joachim, Sayyed, Sufyan Ali, Vielhauer, Volker   +2 more
core   +1 more source

Transitional changes in medication‐initiator cohort profiles in persons with chronic kidney disease and type 2 diabetes—A hospital‐based cohort study in Japan

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To describe temporal changes in the characteristics of medication‐initiator cohorts in persons with chronic kidney disease (CKD) and type 2 diabetes (T2D). Materials and Methods Adults with CKD and T2D initiating sodium‐glucose cotransporter‐2 inhibitors (SGLT‐2i) or glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) were identified in ...
Yuichiro Yano, Suguru Okami, Hiroshi Kanegae, Nikolaus G. Oberprieler, Catherine Johannes, Satoshi Yamashita, Kanae Yoshikawa‐Ryan, Csaba P. Kovesdy, David Vizcaya, Naoki Kashihara   +9 more
wiley   +1 more source

Histopathological characterization of nephritides in the brown capuchin monkey, Cebus apella (Primates: Cebidae)

Revista de Biología Tropical, 2000
The renal lesions are of special importance in the captive primates. The most commonly pathologies are: pyelonephritis, nephrocalcinosis, glomerulonephritis, congenital malformations, hydronephrosis and functional diseases.
Juan T. Borda, Vanessa Nunes-Bastos, Silvia Pérez-Escalá, Marcial Sánchez-Negrette   +3 more
doaj  

Hepatitis C Virus, Cryoglobulinemia, and Kidney: Novel Evidence

Scientifica, 2012
Hepatitis C virus infection can lead to chronic active hepatitis, cirrhosis, and liver failure; however, it is also associated with a wide range of extra-hepatic complications.
Fabrizio Fabrizi
doaj   +1 more source