Results 81 to 90 of about 48,150 (297)

Editorial: Molecular mechanisms of proteinuria, volume II

Frontiers in Medicine, 2022
Ilse S. Daehn, Sandra Merscher
doaj   +1 more source

Comparision of expression ratio of NPHS1, SLC9A3R1 in glomerulus versus tubulointerstitial using real-time PCR.

, 2015
A, Comparision of expression ratio of NPHS1 in isolated glomerulus versus tubulointerstitial; B, Comparision of expression ratio of SLC9A3R1 in tubulointerstitial versus glomerulus (Difference was analysed by Student's t-test, ** indicated P < 0.01).
Jun Tong (821940), Jing Xu (15337), Danfeng Lv (821941), Weijia Zhang (79845), Weiming Wang (158128), Nan Chen (142925), Xiao Li (107004), Jingyuan Xie (156916), Chengguo Wei (128335), Jian Liu (33711), John Cijiang He (322606), Hong Ren (93389), Wen Zhang (7555)   +12 more
core   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

An in-vitro model of the Glomerulus

, 2015
Introduction and Aims: The Glomerulus is the filtration unit of the kidney. It permits retention of high molecular weight proteins in circulation whilst allowing passage to water, small molecules/proteins, sugars and electrolytes.
Johnson, Tim, Tuffin, Jack, Perriman, Adam, Satchell, Simon, Burke, Madeline, Welsh, Gavin, Saleem, Moin   +6 more
core   +1 more source

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Renal progenitor cells: Characterization and genetic manipulations

Current Medicine Research and Practice, 2013
In spite of advances in modern clinical nephrology, progressive renal diseases remain incurable disorders lacking specific therapeutic approaches. It is estimated that 45,000 patients with ESRD (end-stage renal disease) require haemodialysis, with only ...
Kumar Digvijay, Sarah Aijaz, Anurag Gupta, D S Rana   +3 more
doaj  

Sparsened neuronal activity in an optogenetically activated olfactory glomerulus [PDF]

, 2018
© The Author(s), 2018. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Scientific Reports 8 (2018): 14955, doi:10.1038/s41598-018-33021-w.Glomeruli are the functional units ...
Cohen, Lawrence B., Geiller, Tristan, Homma, Ryota, Tombaz, Tuce, Bozza, Thomas, Braubach, Oliver R., Choi, Yunsook   +6 more
core   +1 more source

A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment

Advanced Science, EarlyView.
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu, Huixuan Xu, Li Lin, Fei Wang, Yaodong Ding, Shuangqiao Liao, Xingyu Chen, Jichen Wen, Hongqiang Zhao, Jing Hao, Weixiang Zhao, Gong Zhang, Shiguang Shan, Yong Zeng, Hu Han, Minxian Wang   +15 more
wiley   +1 more source

ROC curves for (a)glomerulus classification and (b) lymphoblast classification using various color texture descriptors.

, 2018
ROC curves for (a)glomerulus classification and (b) lymphoblast classification using various color texture descriptors.
Xingyu Li (5169794), Konstantinos N. Plataniotis (5954471)   +1 more
core   +1 more source

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

Advanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu, Yiyin Rong, Bai Sun, Ziwen Sun, Yifan Wang, Xiaobin Ren, Zelin Cao, Kaikai Gao, Jiawei Yu, Zhenkun Wang, Haoxuan Ma, Jichun Guo, Kai Cao, Mengrun Kang, Songling Wang, Fenggang Ren, Yi Lv, Qiang Lu   +17 more
wiley   +1 more source