Results 131 to 140 of about 33,791,512 (292)

Short‐term clinical responses in horses and ponies treated with canagliflozin: A clinical field study

Equine Veterinary Journal, EarlyView.
Abstract Background Treatment with the sodium‐glucose co‐transporter 2 (SGLT2) inhibitor canagliflozin in insulin dysregulated (ID) horses has shown promising results in randomised clinical trials. Larger field studies are needed to further evaluate treatment responses and potential adverse effects under real‐world conditions.
Moa Hällbom, Sanna Truelsen Lindåse, Monika Wartel, Johan Bröjer   +3 more
wiley   +1 more source

Glucagon‐like peptide‐1 therapy for youth with type 2 diabetes

Journal of Diabetes Investigation, 2023
Young Min Cho
doaj   +1 more source

Dual glucagon recognition by pancreatic beta-cells via glucagon and glucagon-like peptide 1 receptors

, 1998
cAMP is required for normal glucose-induced insulin release by pancreatic beta-cells. In a previous study, we showed that cAMP production in beta-cells depends on the expression of receptors for glucagon, glucagon-like peptide 1(7-36) amide [GLP-1(7-36 ...
Schuit, Frans, Pipeleers, Daniel, Moens, Karen, Van Schravendijk, C, Ling, ZD, Flamez, Daisy   +5 more
core   +1 more source

Probiotic Spore Inspired Oral Drug Delivery System With Multiple‐Barriers‐Crossing Ability Modulates Gut‐Brain Axis for Parkinson's Disease Therapy

Exploration, EarlyView.
Inspired by the germination of probiotic spores, we utilize the excellent characteristics of spores to break through multiple barriers of oral brain‐targeted delivery. Besides the probiotics mediated gut‐brain communication, the spore coat proteins derived nanosystems with multiple‐barriers‐crossing ability alleviate neurodegeneration.
Qianhua Feng, Yuying Mei, Jia Zhang, Liying Sun, Bingqian Si, Huimin Zhou, Huifang Xiao, Runhan Liu, Jieyun Zhang, Lei Wang   +9 more
wiley   +1 more source

Body‐integrated photonic biosensors: Illuminating the path to active healthcare

FlexMat, EarlyView.
Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu, Xingming Wen, Qihang Yan, Yining Zhao, Linghao Yuan, Siyuan Chen, Yue Ma, Zhengyue Fang, Dong Lei, Yuxin Liu, Ze Xiong   +10 more
wiley   +1 more source

Screening and identification of novel peptides stimulating GLP‐1 secretion from plant proteins after simulated gastrointestinal digestion

Food Biomacromolecules, EarlyView.
Effects of digestive products of quinoa, oat, barley, and mungbean proteins on GLP‐1 secretion are investigated using STC‐1 cell and animal experiments, and novel GLP‐1 secretion‐stimulating peptides are successfully identified by column chromatography and LC–MS/MS.
Hongdong Song, Shaoxia Ren, Qiuyun Fu, Lei Xue, Kai Huang, Hongwei Cao, Zetang Zhang, Junhu Li, Xiao Guan   +8 more
wiley   +1 more source

Long-term management of type 2 diabetes with glucagon-like peptide-1 receptor agonists

, 2017
Hamish Courtney,1 Rahul Nayar,2 Chinnadorai Rajeswaran,3 Ravi Jandhyala 4 1Diabetes Department, Royal Victoria Hospital, Belfast, 2City Hospitals Sunderland NHS Foundation Trust, Sunderland, 3Department of Diabetes & Endocrinology, Mid Yorkshire NHS ...
Rajeswaran C, Jandhyala R, Nayar R, Courtney H   +3 more
core  

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

Evaluating preferences for profiles of glucagon-like peptide-1 receptor agonists among injection-naive type 2 diabetes patients in Japan

, 2016
Heather L Gelhorn,1 Elizabeth D Bacci,2 Jiat Ling Poon,1 Kristina S Boye,3 Shuichi Suzuki,4 Steven M Babineaux3 1Outcomes Research, Evidera, Bethesda, MD, 2Evidera, Seattle, WA, 3Global Patient Outcomes and Real World Evidence, Eli Lilly and Company ...
Suzuki S, Boye KS, Babineaux SM, Bacci ED, Gelhorn HL, Poon JL   +5 more
core  

Standardized Research Methodology for Akkermansia muciniphila: Multi‐Omics Integration, Functional Evaluation, and Clinical Translation Pathways

Gut Medicine, EarlyView.
ABSTRACT Background Akkermansia muciniphila has emerged as a leading next‐generation beneficial microbe candidate in gut microbiome research, linked to host metabolic homeostasis, mucosal immune regulation, and intestinal barrier integrity. However, marked methodological heterogeneity in isolation and culture conditions, detection and quantification ...
Jiaxin Chen, Mantang Qiu
wiley   +1 more source