Results 221 to 230 of about 76,287 (255)

Glucagon-Like Peptide 1—A Cardiologic Dimension

Trends in Cardiovascular Medicine, 2010
Recent experimental data suggest glucagon-like peptide 1 (GLP-1) and its analogs to have direct effects on the cardiovascular system, in addition to their classic glucoregulatory actions. These direct effects may be cardioprotective, contractility augmenting, and vasorelaxant.
Treiman, Marek, Elvekjaer, Mikkel, Engstrøm, Thomas, Jensen, Jan Skov   +3 more
openaire   +3 more sources

Glucagon-like peptide-1 receptor

Current Biology
Michael Krashes discusses glucagon-like peptide-1 receptors, their physiological role in glucose metabolism and the mode of action of their agonists that are used to treat obesity and were later shown to promote weight loss.
openaire   +2 more sources

Glucagon-like peptide-1 medicines and cancer

Nature Cancer
Glucagon-like peptide-1 (GLP-1) medicines reduce food intake, body weight, insulin resistance and inflammation, thus improving outcomes for people with type 2 diabetes and obesity and potentially contributing to decreased cancer incidence. GLP-1 medicines acting through weight loss-dependent and weight loss-independent mechanisms hold potential for ...
Julian M. Yabut, Daniel J. Drucker
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Glucagon-Like Peptide 1 and the Cardiovascular System

Current Diabetes Reviews, 2014
Glucagon-like peptide 1 (GLP1) is a major incretin hormone. This means that it is secreted by the gut in response to food and helps in reducing post-prandial glucose exertion. It achieves this through a number of mechanisms, including stimulating insulin release by pancreatic β-cells in a glucose-dependent manner; inhibition of glucagon release by ...
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Glucagon and Glucagon-Like Peptides 1 and 2

2009
The glucagon gene is expressed not only in the alpha cells of the pancreatic islets but also in the endocrine cells of the intestinal epithelium (so-called L-cells), and in certain neurons of the brain stem. Whereas in the pancreas, glucagon, the hyperglycaemic hormone, is cleaved out of the 160 amino acid precursor, proglucagon, leaving behind ...
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Glucagon-like peptide-1

2006
  +4 more sources

Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets

Diabetologia, 1985
W E Schmidt, Siegel E G, Creutzfeldt W
exaly  

Glucagon-like peptide-1, a new hormone of the entero-insular axis

Diabetologia, 1992
Ørskov C, C Ørskov
exaly  

A Glucagon-Like Peptide-1 Analog Reverses the Molecular Pathology and Cardiac Dysfunction of a Mouse Model of Obesity

Circulation, 2013
Ren-Ke Li, Filio Billia, Mansoor Husain   +2 more
exaly  

Glucagon-like peptide-1

2021
openaire   +1 more source