Results 161 to 170 of about 76,287 (256)

Trends of Obesity in Early Adulthood and Later Adulthood Across 196 Countries and Territories, 1990–2022

open access: yesObesity, EarlyView.
ABSTRACT Objective We aimed to understand the global burden of obesity in early adulthood and later adulthood over the past three decades. Methods We analyzed obesity prevalence across 196 countries/territories from 1990 to 2022 for early adulthood (age 20–49 years) and later adulthood (age ≥ 50 years) using the Non‐Communicable Disease Risk Factor ...
Abdiwahab M. Ali   +2 more
wiley   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists for Obstructive Sleep Apnea With and Without Continuous Positive Airway Pressure

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate glucagon‐like peptide 1 receptor agonists for obstructive sleep apnea compared with controls. Data Sources CINAHL, Cochrane Library, PubMed, and Scopus. Review Methods A PRISMA‐compliant search was conducted from database inception through October 2025.
Cali Loblundo   +3 more
wiley   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen   +5 more
wiley   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

open access: yesPrecision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman   +3 more
wiley   +1 more source

Cancer Incidence Among Users of Glucagon-Like Peptide-1 Receptor Agonists. [PDF]

open access: yesJ Gen Intern Med
Rashid Z   +8 more
europepmc   +1 more source

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