Results 131 to 140 of about 140,006 (312)

Current perspective on the role of insulin and glucagon in the pathogenesis and treatment of type 2 diabetes mellitus

, 2019
Ashutosh Ojha,1 Utkarsh Ojha,2 Raihan Mohammed,3 Abhinaya Chandrashekar,2 Harsh Ojha41Shobhaben Pratapbhai Patel School Of Pharmacy & Technology Management, SVKM’s Narsee Monjee Institute of Management Studies, Mumbai, India; 2Faculty of ...
Ojha A, Mohammed R, Ojha H, Ojha U, Chandrashekar A   +4 more
core  

Editorial: The Role of Neuropeptides in Drug Addiction and Other Psychiatric Disorders

Frontiers in Behavioral Neuroscience, 2022
Kabirullah Lutfy, Lucia Hipolito, Valentina Ferretti, Leandro F. Vendruscolo, Marsida Kallupi   +4 more
doaj   +1 more source

A protein-rich meal provides beneficial glycemic and hormonal responses as compared to meals enriched in carbohydrate, fat or fiber, in individuals with or without type-2 diabetes

Frontiers in Nutrition
IntroductionDiet stands as a pivotal modifiable risk factor influencing weight gain and the onset of type-2 diabetes (T2D). This study delves into the variation in glucose and regulatory pancreatic hormone levels subsequent to the consumption of meals ...
Neda Rajamand Ekberg, Neda Rajamand Ekberg, Sergiu-Bogdan Catrina, Sergiu-Bogdan Catrina, Peter Spégel   +4 more
doaj   +1 more source

Body‐integrated photonic biosensors: Illuminating the path to active healthcare

FlexMat, EarlyView.
Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu, Xingming Wen, Qihang Yan, Yining Zhao, Linghao Yuan, Siyuan Chen, Yue Ma, Zhengyue Fang, Dong Lei, Yuxin Liu, Ze Xiong   +10 more
wiley   +1 more source

Miniglucagon [glucagon-(19-29)] is a component of the positive inotropic effect of glucagon

, 1991
Glucagon is well known for its cardiotonic effect, but its mechanism of action remains undetermined. In the present study, we showed that glucagon, under minimal degradation conditions, had no effect on the amplitude of contractility of beating chick ...
V. Brechler, S. Laurent, C. Pavoine, P. Blache, D. Le-Nguyen, F. Pecker, D. Bataille, A. Kervran   +7 more
core   +1 more source

The integrated incretin effect is reduced by both glucose intolerance and obesity in Japanese subjects

Frontiers in Endocrinology
IntroductionIncretin-based drugs are extensively utilized in the treatment of type 2 diabetes (T2D), with remarkable clinical efficacy. These drugs were developed based on findings that the incretin effect is reduced in T2D.
Akihiro Hamasaki, Akihiro Hamasaki, Norio Harada, Atsushi Muraoka, Shunsuke Yamane, Erina Joo, Kazuyo Suzuki, Nobuya Inagaki   +7 more
doaj   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

Glucagon-like peptide-1 receptor activation in the nucleus accumbens core suppresses feeding by increasing glutamatergic AMPA/Kainate signaling

, 2014
Glucagon-like peptide-1 receptor (GLP-1R) activation in the nucleus accumbens (NAc) core is pharmacologically and physiologically relevant for regulating palatable food intake.
Elizabeth G. Mietlicki-Baase (4586044), James E. McCutcheon (7631261), Mitchell F. Roitman (7639346), Matthew R. Hayes (4586035), Christopher G. Sinon (7650542), Pavel I. Ortinski (3185358), David J. Reiner (7650539), R. Christopher Pierce (7650545)   +7 more
core  

Impact of Gut Microbiota Metabolites on Serotonin Levels in Irritable Bowel Syndrome

Gut Medicine, EarlyView.
ABSTRACT Gut microbiota and their metabolites have been proposed as possible etiological factors in irritable bowel syndrome (IBS), and studies suggest that IBS is associated with impaired serotonin synthesis and release. Microbial metabolites are produced through biological pathways and enzymatic processes via gut microbiota.
Ning Gao, Yu Liu, Shaoxin Sun, Lulu Bin, Shanshan Li, Tao Yang, Winson Fu Zun Yang, Jiani Wu   +7 more
wiley   +1 more source