The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda +215 more
core +1 more source
Cell type-specific differences in β-glucan recognition and signalling in porcine innate immune cells [PDF]
β-glucans exert receptor-mediated immunomodulating activities, including oxidative burst activity and cytokine secretion. The role of the β-glucan receptors dectin-1 and complement receptor 3 (CR3) in the response of immune cells towards β-glucans is ...
Adachi +55 more
core +2 more sources
Hsp90 governs dispersion and drug resistance of fungal biofilms [PDF]
Fungal biofilms are a major cause of human mortality and are recalcitrant to most treatments due to intrinsic drug resistance. These complex communities of multiple cell types form on indwelling medical devices and their eradication often requires ...
A Lupetti +69 more
core +9 more sources
Beta-D-Glucan in Patients with Haematological Malignancies
(1-3)-beta-D-glucan (BDG) is an almost panfungal marker (absent in zygomycetes and most cryptococci), which can be successfully used in screening and diagnostic testing in patients with haematological malignancies if its advantages and limitations are ...
Malgorzata Mikulska +3 more
doaj +1 more source
The role of octadecanoids and functional mimics in soybean defense responses [PDF]
Oxylipins of the jasmonate pathway and synthetic functional analogs have been analyzed for their elicitor like activities in an assay based on the induced accumulation of glyceollins, the phytoalexins of soybean (Glycine max L.), in cell suspension ...
Czarnecka E. +7 more
core +1 more source
Identification of New Antifungal Agents Targeting Chitin Synthesis by a Chemical-Genetic Method
Fungal infection is a leading cause of mortality in immunocompromised population; thus, it is urgent to develop new and safe antifungal agents. Different from human cells, fungi have a cell wall, which is composed mainly of polysaccharide glucan and ...
Yan Li +5 more
doaj +1 more source
Conformational studies of β‐glucans [PDF]
AbstractSteric and energy contour diagrams have been plotted for disaccharide‐like and for helical structures of linear β‐D‐glucans having (1 → 2), (1 → 3) and (1 → 4) linkages. The allowed conformations constitute only about. 4% of the total conformations, indicating that the freedom of rotation of glucose residues is highly restricted in all the ...
B K, Sathyanarayana, V S, Rao
openaire +2 more sources
Glucan rich nutrition does not increase gut translocation of beta‐glucan [PDF]
AbstractBackground(1‐3)‐b‐D‐glucan (BDG) is a fungal cell wall component and, in the absence of invasive fungal infection, a novel biomarker for microbial translocation of endogenous fungal products from the gastrointestinal tract into systemic circulation.
Martin Hoenigl +12 more
openaire +4 more sources
Development of Fish Immunity and the Role of β-Glucan in Immune Responses
Administration of β-glucans through various routes, including immersion, dietary inclusion, or injection, have been found to stimulate various facets of immune responses, such as resistance to infections and resistance to environmental stress.
Marianna V. Rodrigues +5 more
doaj +1 more source
Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining [PDF]
This work was supported by the European Commission within the FP7 Framework Programme [Fungitect-Grant No 602125]. We also thank Thomas Sauer, Vienna Biocenter Campus (VBC), Austria, for technical support at the FACS facility of the MFPL, Karl Kuchler ...
Gow, N +5 more
core +1 more source

