A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun +13 more
wiley +1 more source
Heterogeneity of lymphoid cells in PBMCs in the acute phase of SFTS: Single-cell transcriptome profiling. [PDF]
Zhao J +12 more
europepmc +1 more source
Hair cortisol concentrations are associated with hippocampal subregional volumes in children
Bender, A. +5 more
core +1 more source
Revisiting the Ethics of Urate‐Lowering Therapy Clinical Trials for Gout Management
Arthritis &Rheumatology, EarlyView.
Lisa K. Stamp, Dien Ho, Nicola Dalbeth
wiley +1 more source
Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis +11 more
wiley +1 more source
A natural history study of Chinese individuals with Duchenne muscular dystrophy: Results from 2 years of follow-up and beyond. [PDF]
Li X +10 more
europepmc +1 more source
Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt +18 more
wiley +1 more source
RETRACTION: Xiao Yao San against Corticosterone-Induced Stress Injury via Upregulating Glucocorticoid Receptor Reaction Element Transcriptional Activity. [PDF]
And Alternative Medicine EC.
europepmc +1 more source
卵巣内におけるSerum- and glucocorticoid-regulated kinase (SGK)による細胞内pH上昇とcyclin B-Cdk1活性化を介したヒトデ卵第一減数分裂の制御機構[学位論文内容の要旨/学位論文審査の要旨/日本語要旨/外国語要旨] [PDF]
絵奈子 細田
openalex

