Results 151 to 160 of about 3,524 (210)
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Best Practice & Research Clinical Rheumatology, 2011
Glucocorticoids remain part of the treatment strategy in many rheumatic diseases, because of their anti-inflammatory and immunosuppressive actions. Unfortunately, their clinically desired effects are linked to adverse effects, especially at higher dosages and longer duration of treatment.
Cornelia M, Spies +4 more
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Glucocorticoids remain part of the treatment strategy in many rheumatic diseases, because of their anti-inflammatory and immunosuppressive actions. Unfortunately, their clinically desired effects are linked to adverse effects, especially at higher dosages and longer duration of treatment.
Cornelia M, Spies +4 more
openaire +4 more sources
Annals of the New York Academy of Sciences, 2004
A bstract : Epidemiological evidence suggests that an adverse fetal environment permanently programs physiology, leading to increased risks of cardiovascular, metabolic, and neuroendocrine disorders in adulthood.
Jonathan R, Seckl, Michael J, Meaney
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A bstract : Epidemiological evidence suggests that an adverse fetal environment permanently programs physiology, leading to increased risks of cardiovascular, metabolic, and neuroendocrine disorders in adulthood.
Jonathan R, Seckl, Michael J, Meaney
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Annals of the New York Academy of Sciences, 2006
Abstract: Disease modifying antirheumatic drugs (DMARDs) are drugs used in rheumatoid arthritis (RA) to control the disease and to limit joint damage and improve long‐term outcome. The last decade evidence has accumulated that suggests that low dosages of glucocorticoids are indeed able to control the disease and limit the destruction.
Bijlsma, Johannes W J +4 more
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Abstract: Disease modifying antirheumatic drugs (DMARDs) are drugs used in rheumatoid arthritis (RA) to control the disease and to limit joint damage and improve long‐term outcome. The last decade evidence has accumulated that suggests that low dosages of glucocorticoids are indeed able to control the disease and limit the destruction.
Bijlsma, Johannes W J +4 more
openaire +2 more sources
2016
The most effective anti-inflammatory drugs used to treat patients with airways disease are topical glucocorticosteroids (GCs). These act on virtually all cells within the airway to suppress airway inflammation or prevent the recruitment of inflammatory cells into the airway.
Adcock, IM, Mumby, S
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The most effective anti-inflammatory drugs used to treat patients with airways disease are topical glucocorticosteroids (GCs). These act on virtually all cells within the airway to suppress airway inflammation or prevent the recruitment of inflammatory cells into the airway.
Adcock, IM, Mumby, S
openaire +3 more sources
Glucocorticoids and Osteoporosis
Endocrinology and Metabolism Clinics of North America, 1994In summary, patients who will remain on glucocorticoids for more than a few weeks are clearly at risk for osteoporosis. A list of therapeutic strategies is provided in Table 2. While our therapy remains inadequate at this time, newer agents are on the horizon.
R A, Adler, C J, Rosen
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Veterinary Dermatology, 2008
AbstractGlucocorticoids are one of the two main classes of hormones, along with mineralocorticoids, which are secreted from the adrenal cortex. Since the discovery of the anti‐inflammatory properties of the natural glucocorticoid hydrocortisone, a large number of artificial glucocorticoids have been synthesized to attempt to increase efficacy and ...
Andrew D, Lowe +2 more
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AbstractGlucocorticoids are one of the two main classes of hormones, along with mineralocorticoids, which are secreted from the adrenal cortex. Since the discovery of the anti‐inflammatory properties of the natural glucocorticoid hydrocortisone, a large number of artificial glucocorticoids have been synthesized to attempt to increase efficacy and ...
Andrew D, Lowe +2 more
openaire +2 more sources
Current Opinion in Rheumatology, 1989
Despite the continuing debate about the risks and benefits of glucocorticoid, their central role in the therapeutic armamentarium remains undisputed. Studies continue to unravel the complexity of their biologic effects on gene transcription, and careful clinical observation refines their therapeutic use.
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Despite the continuing debate about the risks and benefits of glucocorticoid, their central role in the therapeutic armamentarium remains undisputed. Studies continue to unravel the complexity of their biologic effects on gene transcription, and careful clinical observation refines their therapeutic use.
openaire +3 more sources
Glucocorticoids and the Osteoclast
Annals of the New York Academy of Sciences, 2007Abstract: Glucocorticoid (GC)‐induced bone loss is the most common cause of secondary osteoporosis but its pathogenesis is controversial. GCs clearly suppress bone formation in vivo but the means by which they impact osteoblasts is unclear. Because bone remodeling is characterized by tethering of the activities of the two cells, the osteoclast is a ...
Hyun-Ju, Kim +7 more
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2014
Glucocorticoids are the most effective anti-inflammatory treatment for allergic diseases, and inhaled glucocorticoids have now become the first-line treatment for asthma. Glucocorticoids were discovered in the 1940s as extracts of the adrenal cortex and this was followed by the isolation of adrenocorticotropic hormone (ACTH) from pituitary gland ...
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Glucocorticoids are the most effective anti-inflammatory treatment for allergic diseases, and inhaled glucocorticoids have now become the first-line treatment for asthma. Glucocorticoids were discovered in the 1940s as extracts of the adrenal cortex and this was followed by the isolation of adrenocorticotropic hormone (ACTH) from pituitary gland ...
openaire +2 more sources