Results 141 to 150 of about 31,658 (264)

Semaglutide impacts skeletal muscle to a similar extent as caloric restriction in mice with diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend Four weeks of semaglutide treatment causes significant reductions in total body weight, fat mass, lean mass, and grip strength in mice with diet induced obesity. Mice treated with semaglutide lost a greater amount of total body weight and fat mass compared to mice fed fed a calorie matched diet.
S. Jeromson, B. Baranowski, M. Akcan, B. D. Waters, K. Eisner, A. Bellucci, S. Trang, A. Abolhassani, M. A. Tello‐Palencia, A. Schweitzer, B. Stefanska, C. J. Mitchell, David C. Wright   +12 more
wiley   +1 more source

Excessive training does not induce mitochondrial dysfunction or impair insulin signalling within skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of overtraining in trained endurance athletes reduced exercise performance without impairing glucose tolerance. In skeletal muscle, overtraining was associated with increased expression of lipid metabolism‐related proteins, enhanced mitochondrial biogenesis and preserved insulin signalling, despite elevated oxidative ...
Geneviève J. DesOrmeaux, Henver S. Brunetta, Pierre‐Andre Barbeau, Alexandra M. Coates, Christopher Pignanelli, Fasih A. Rahman, Jamie F. Burr, Graham P. Holloway   +7 more
wiley   +1 more source

Abcc1 deficiency protects from corticosterone but not cortisol‐induced adiposity and insulin resistance in a sex‐specific manner

The Journal of Physiology, EarlyView.
Abstract figure legend A mouse model of exogenous glucocorticoid (GC) treatment was used to determine (1) if corticosterone induced the same metabolic dysregulation as cortisol, and (2) whether these differences were mediated by the corticosterone‐specific transmembrane exporter Abcc1.
Mhairi A. Paul, Boglarka Nagy, Sofia Laforest, Joanna P. Simpson, William Mungall, Natalie Z. M. Homer, Robert K. Semple, Ruth Andrew, Roland H. Stimson, Mark Nixon   +9 more
wiley   +1 more source

Using of the Glucometers Serial Interface by Sightless People

Advances in Electrical and Electronic Engineering, 2005
Many of the personal diagnostic systems mainly glucometers (for measuring glucose) contain a serial interface for PC connection. Through this interface it is possible to receive useful data that will be used mainly for an attending physician’s purpose to
Lukas Martinak, Marek Penhaker
doaj  

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

The Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild, Valdemar Brimnes Ingemann Johansen, Christoffer Clemmensen, Pablo Ranea‐Robles   +3 more
wiley   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

The Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli, Petras Minderis, Andrej Fokin, Aivaras Ratkevicius, Ingrida Balnyte, Polzonetti Valeria, Tomas Venckunas, Cameron Hill, Danguole Satkunskiene, Hans Degens   +9 more
wiley   +1 more source

Antidiabetic Effect of Tiger Nut and Coconut Blend in Experimental Type 2 Diabetic Rat Model

Phytochemicals in Food and Medicine, Volume 1, Issue 4, December 2026.
The combination of tiger nut and coconut demonstrated antihyperglycemic, antihyperlipidemic, anti‐inflammatory, and antioxidant activities on type 2 diabetic rat model over a 4‐week treatment period. ABSTRACT Tiger nut and coconut are chewy and popularly consumed as food either alone, mixed, or paired with other fruits, seeds, and vegetables.
Aminu Mohammed, Mubarak Labaran Liman
wiley   +1 more source

Experiences of Patients Living with Complications of Noncommunicable Diseases  in Mzuzu, Malawi

Public Health Challenges, Volume 5, Issue 4, December 2026.
The study investigates the experiences of noncommunicable disease (NCD) patients living with complications in Mzuzu, Malawi, focusing on sanitation issues. Through in‐depth interviews with nine individuals, it reveals a lack of modern facilities and sanitation education.
Mary Kumwanje, Thokozani Mzumara, Isaac Ndemera   +2 more
wiley   +1 more source

Metabolic Changes During a Calorie‐Restricted, Fish‐Rich Ketogenic Diet Associated With Increased Circulating TMAO in Healthy Adults

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
A 2‐week calorie‐restricted, fish‐rich ketogenic diet increased circulating TMAO while improving selected glycemic and insulin‐related biomarkers in healthy adults. HDL cholesterol decreased, whereas oxidative stress markers remained unchanged, highlighting a complex short‐term metabolic response that should not be interpreted as evidence of causality.
Katarzyna Siedzik, Kamil Góral, Damian Flis, Maciej Jaguszewski, Robert A. Olek, Wiesław Ziółkowski   +5 more
wiley   +1 more source