Results 11 to 20 of about 171,466 (287)
Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in db/db Mice
Cells, 2022 Aquaporin-9 (AQP9) is a facilitator of glycerol and other small neutral solute transmembrane diffusion. Identification of specific inhibitors for aquaporin family proteins has been difficult, due to high sequence similarity between the 13 human isoforms,
Marilina Florio +11 more
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Differential Metabolism of Glycerol Based on Oral versus Intravenous Administration in Humans
Metabolites, 2022 Glycerol can be metabolized to glucose via gluconeogenesis or lactate via glycolysis. It is unknown if glycerol is metabolized similarly in the portal and systemic circulations in humans.
Ankit Shah +2 more
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The molecular mechanism of propionate-regulating gluconeogenesis in bovine hepatocytes [PDF]
Animal Bioscience, 2023 Objective Cows that are nursing get around 80% of their glucose from liver gluconeogenesis. Propionate, a significant precursor of liver gluconeogenesis, can regulate the key genes involved in hepatic gluconeogenesis expression, but its precise effects ...
Rui Pang +7 more
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Cells, 2023 Nanomaterials offer a broad spectrum of applications in biomedicine. The shapes of gold nanoparticles could modulate tumor cell behavior. Spherical (AuNPsp), stars (AuNPst) and rods (AuNPr) shapes of polyethylene glycol coated-gold nanoparticles (AuNPs ...
Sílvia Soares +7 more
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Optimized 3D Culture of Hepatic Cells for Liver Organoid Metabolic Assays
Cells, 2021 The liver is among the principal organs for glucose homeostasis and metabolism. Studies of liver metabolism are limited by the inability to expand primary hepatocytes in vitro while maintaining their metabolic functions.
Christian Moya Gamboa +5 more
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Animal, 2020 Since nutritional requirements are increased at the end of gestation to meet the demands of the pregnant uterus, pregnant beef cows are susceptible to mobilization of body reserves (mainly fat and amino acids (AAs)) and to alter the metabolism of ...
R.C. Lopes +8 more
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Veterinary Research, 2020 Brucella ovis is a non-zoonotic rough Brucella that causes genital lesions, abortions and increased perinatal mortality in sheep and is responsible for important economic losses worldwide. Research on virulence factors of B.
Nieves Vizcaíno +5 more
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Against the stream: relevance of gluconeogenesis from fatty acids for natives of the arctic regions [PDF]
International Journal of Circumpolar Health, 2012 Background. The question whether even-chain fatty acids can be converted into glucose has a long-standing tradition in biochemistry. Since the glyoxylate shunt is absent from mammals, the question has been considered to be solved.
Stefan Schuster +2 more
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Frontiers in Nutrition, 2023 IntroductionFood proteins have been recognized as an ideal source to release bioactive peptides with the potential to intervene nutrition related chronic diseases, such as cardiovascular diseases, obesity and diabetes.
Wang Liao +5 more
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Cell Reports, 2020 Summary: Isotope-based assessment of metabolic flux is achieved through a judicious balance of measurements and assumptions. Recent publications debate the validity of key assumptions used to model stable isotope labeling of liver metabolism in vivo ...
Clinton M. Hasenour +2 more
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