Results 201 to 210 of about 3,865 (217)
Some of the next articles are maybe not open access.
Calcium affects glucoraphanin metabolism in broccoli sprouts under ZnSO4 stress
Food Chemistry, 2021CaCl2, Ca2+ chelator (EGTA) and Ca2+ channel blocker (verapamil) were used to investigate mechanism of glucoraphanin metabolism in broccoli sprouts under ZnSO4 stress. CaCl2 treatment promoted sprout growth, reduced MDA (malonaldehyde) content and electrolyte leakage in sprouts under ZnSO4 stress.
Li, Zhuang +5 more
openaire +2 more sources
Evaluation of the safety and bioactivity of purified and semi-purified glucoraphanin
Food and Chemical Toxicology, 2008The anti-carcinogenic effects of broccoli have been attributed to sulforaphane, the hydrolysis product of glucoraphanin (GRP). Here we determined if purified GRP, in the absence of the plant-derived hydrolyzing enzyme myrosinase, could affect pulmonary and hepatic ethoxyresorufin O-deethylase (EROD) and/or NAD(P)H-quinone oxidoreductase 1 (NQO1 ...
R-H, Lai +4 more
openaire +2 more sources
The synthesis of isotopically labelled glucoraphanin for metabolic studies
Tetrahedron Letters, 2007Abstract The first synthesis of a stable isotopically labelled derivative of the glucosinolate glucoraphanin, namely [10- 13 C,11,12- 2 H 5 ]glucoraphanin, is described. This also represents the first total chemical synthesis of glucoraphanin itself.
John J. Morrison, Nigel P. Botting
openaire +1 more source
Glucoraphanin hydrolysis by microbiota in the rat cecum results in sulforaphane absorption
Food & Function, 2010In the absence of the plant enzyme myrosinase, such as in cooked broccoli, glucoraphanin is considered to be hydrolyzed by bacteria in the lower gut to produce the bioactive isothiocyanate sulforaphane. Simulated digestion using US Pharmacopeia methods caused no loss of glucoraphanin, confirming that glucoraphanin is not destroyed by digestive enzymes ...
Ren-Hau, Lai +2 more
openaire +2 more sources
Physiology and Molecular Biology of Plants, 2022
Sulforaphane (SF) is one of the most effective natural products in preventing and fighting cancer, found in cruciferous plants. In this study, broccoli hairy roots grown for 20 d were used as the experimental material, and it was treated with 500 μmol/L melatonin (MT) for 0, 12 and 32 h to explore the effect of MT on the conversion of glucoraphanin ...
Xiaoling Zhang +7 more
openaire +2 more sources
Sulforaphane (SF) is one of the most effective natural products in preventing and fighting cancer, found in cruciferous plants. In this study, broccoli hairy roots grown for 20 d were used as the experimental material, and it was treated with 500 μmol/L melatonin (MT) for 0, 12 and 32 h to explore the effect of MT on the conversion of glucoraphanin ...
Xiaoling Zhang +7 more
openaire +2 more sources
Engineering of methionine chain elongation part of glucoraphanin pathway in E. coli
Metabolic Engineering, 2016The methionine-derived glucosinolate glucoraphanin is associated with the health-promoting properties of broccoli. This has developed a strong interest in producing this compound in high amounts from a microbial source. Glucoraphanin synthesis starts with a five-gene chain elongation pathway that converts methionine to dihomo-methionine, which is ...
Mirza, Nadia Muhammad Akram +3 more
openaire +3 more sources
Bioorganic & Medicinal Chemistry Letters, 1999
A new semi-synthetic way to produce glucoraphanin (2), the bio-precursor of the potential anticarcinogen sulforaphane (3), has been developed. Starting from glucoerucin (1), isolated from ripe seeds of Eruca sativa, glucoraphanin was obtained through chemoselective oxidation.
R, Iori +4 more
openaire +2 more sources
A new semi-synthetic way to produce glucoraphanin (2), the bio-precursor of the potential anticarcinogen sulforaphane (3), has been developed. Starting from glucoerucin (1), isolated from ripe seeds of Eruca sativa, glucoraphanin was obtained through chemoselective oxidation.
R, Iori +4 more
openaire +2 more sources
Analytica Chimica Acta, 2010
Glucoraphanin, a glucosinolate, is found naturally in plants and is present in relatively high concentrations in broccoli. Glucosinolates have received much attention as studies have indicated that a diet rich in them may provide some protection from certain cancers.
Iris, Lee +2 more
openaire +2 more sources
Glucoraphanin, a glucosinolate, is found naturally in plants and is present in relatively high concentrations in broccoli. Glucosinolates have received much attention as studies have indicated that a diet rich in them may provide some protection from certain cancers.
Iris, Lee +2 more
openaire +2 more sources
Collard landraces are novel sources of glucoraphanin and other aliphatic glucosinolates
Plant Breeding, 2015AbstractThe glucosinolate make‐up of the edible parts of some Brassica oleracea L. crops has been investigated previously, but the leafy‐green collard (B. oleracea var. viridis) remains relatively unstudied on this topic. Due to this lack of information, a collection of US landraces was examined for glucosinolate content of leaves.
Zachary Stansell +3 more
openaire +1 more source
Glucoraphanin and sulforaphane evolution during juice preparation from broccoli sprouts
Food Chemistry, 2018Broccoli sprouts are considered functional food as they are naturally enriched in glucoraphanin (GR) that is the biological precursor of the anticancer compound sulforaphane (SFN). Due to its health promoting value, also broccoli sprout juice is becoming very popular.
Cristiano Bello +4 more
openaire +2 more sources