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Integrating Cartilage Explant Culture with Simulated Digestion and Hepatic Biotransformation Refines In Vitro Screening of Joint Care Nutraceuticals [PDF]
Methods and ProtocolsIn vitro cartilage explant culture has been used to assess nutraceuticals on cartilage responses to inflammatory stimuli. However, applying extracts of nutraceuticals directly to cartilage explants does not account for effects of digestion and hepatic ...
Michelina Crosbie +3 more
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Association of habitual glucosamine use with risk of microvascular complications among individuals with type 2 diabetes: a prospective cohort study in UK biobank [PDF]
Nutrition & DiabetesBackground Glucosamine is a widely used supplement for treating osteoarthritis and joint pain. New evidence suggests a potential association between glucosamine and type 2 diabetes, inflammation and cardiometabolic risk.
Zi-Jian Cheng +9 more
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Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study [PDF]
Frontiers in EndocrinologyBackgroundEvidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. However, the causal relationship remains uncertain.
Yi Kang +8 more
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Crystals, 2023 Glucosamine is a natural drug widely used for treating osteoarthritis and is usually left until it expires, which will cause a waste of resources if treated as garbage.
Lijuan Feng +6 more
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The biosynthesis of glucosamine [PDF]
Biochimica et Biophysica Acta, 1953 Abstract A partially purified enzyme has been prepared from Neurospora crassa which catalyzes the formation of glucosamine phosphate from hexose-6-phosphate and glutamine. The glucosamine phosphate was identified by colour reactions, by dephosphorylation and paper chromatography and by its behaviour towards an acetylating system.
Leloir, Luis Federico +1 more
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Who uses glucosamine and why? A study of 266,848 Australians aged 45 years and older. [PDF]
PLoS ONE, 2012 OBJECTIVES: There has been a dramatic increase in the use of complementary medicines over recent decades. Glucosamine is one of the most commonly used complementary medicines in Western societies.
David Sibbritt +4 more
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Application and Research Progress of Glucosamine in Health Food
Shipin gongye ke-ji, 2023 An aging society is coming in China with more and more serious problems such as osteoporosis and osteoarthritis. Glucosamine is one of important components from proteoglycan in human articular cartilage matrix, which can improve articular cartilage ...
Hailin CHI +3 more
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Human Nutrition & Metabolism, 2021 d-Glucosamine is a protective dietary supplement or medicine for osteoarthritis of the knee, a musculoskeletal disease that leads to a significant deterioration in daily activities and quality of life.
Hideya Shintani +2 more
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