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Annals of Pharmacotherapy, 1998
OBJECTIVE: To review the pharmacology and pharmacokinetics of glucosamine and critically evaluate currently available literature regarding its safety and efficacy. DATA SOURCE: A MEDLINE search was conducted between January 1965 and May 1997. Key words used in the search were osteoarthritis, osteoarthrosis, gonarthrosis, and glucosamine.
T S, Barclay, C, Tsourounis, G M, McCart
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OBJECTIVE: To review the pharmacology and pharmacokinetics of glucosamine and critically evaluate currently available literature regarding its safety and efficacy. DATA SOURCE: A MEDLINE search was conducted between January 1965 and May 1997. Key words used in the search were osteoarthritis, osteoarthrosis, gonarthrosis, and glucosamine.
T S, Barclay, C, Tsourounis, G M, McCart
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Glucosamine and Chondroitin Sulfate [PDF]
Rheumatic Disease Clinics of North America, 2011 Glucosamine and chondroitin sulfate, components of normal cartilage that are marketed as dietary supplements in the United States, have been evaluated for their potential role in the treatment of osteoarthritis. Due to claims of efficacy, increased prevalence of osteoarthritis, and a lack of other effective therapies, there has been substantial ...
Daniel O. Clegg +2 more
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Glucosamine and Glucosamine-Peptides Antimicrobial Compounds
2015Bacterial resistance to chemical and physical methods in food processing, and the consumers’ demand for food free of chemical additives challenge the food industry to identify new approaches for food preservation. Affordable and novel antimicrobial compounds from food derived sources are an interesting field of research.
Hincapie Martinez, Daylin J
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Glucosamine and osteoarthritis [PDF]
Future Rheumatology, 2006 Osteoarthritis is the most common form of arthritis and is commonly associated with significant disability. Glucosamine is widely used by patients with osteoarthritis as a nutriceutical in the USA and as a pharmaceutical in Europe. The efficacy of oral glucosamine, with regard to both symptom and disease modification in patients with osteoarthritis ...
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2003
In the 1950s, in vitro studies of glucosamine demonstrated its potential to increase fibroblast production of collagen and mucopolysaccharides. These findings led to studies of glucosamine for the treatment of osteoarthritis (OA) in humans, first with an injectable product, and then with oral supplementation (McCarty, 1994).
Timothy S. Tracy, Melanie Johns Cupp
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In the 1950s, in vitro studies of glucosamine demonstrated its potential to increase fibroblast production of collagen and mucopolysaccharides. These findings led to studies of glucosamine for the treatment of osteoarthritis (OA) in humans, first with an injectable product, and then with oral supplementation (McCarty, 1994).
Timothy S. Tracy, Melanie Johns Cupp
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Medical Hypotheses, 1997
Amphiregulin and transforming growth factor-alpha, agonists for the epidermal growth factor receptor, are the major autocrine growth factors for cultured keratinocytes, and their substantial overexpression in psoriatic lesions suggests that they are crucial to the basal hyperplasia that characterizes psoriasis. Amphiregulin binds to heparin and related
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Amphiregulin and transforming growth factor-alpha, agonists for the epidermal growth factor receptor, are the major autocrine growth factors for cultured keratinocytes, and their substantial overexpression in psoriatic lesions suggests that they are crucial to the basal hyperplasia that characterizes psoriasis. Amphiregulin binds to heparin and related
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GLUCOSAMINE IN THE TREATMENT OF OSTEOARTHRITIS
Rheumatic Disease Clinics of North America, 2000Glucosamine sulfate, a constituent of cartilage, is evaluated for the treatment of osteoarthritis. Available data suggest that glucosamine decreases pain and improves function in osteoarthritis. Most of the glucosamine studies have methodological flaws or used parenteral formulations, making their data difficult to extrapolate into clinical practice ...
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Exhaustive Methylation of Glucosamine
Journal of Pharmaceutical Sciences, 1961A reported synthesis of a glucosamine quaternary derivative was investigated by chemical and infrared spectra methods. Under the conditions reported the glucosamine was found to become degraded and tetramethylammonium iodide was formed.
Bernard Ecanow +2 more
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Enzymatic Microdetermination of D-Glucosaminate with D-Glucosaminate Dehydratase
Analytical Letters, 1982Abstract A simple spectrophotometric method for the dectermination of D-glucosaminate with bacterial D-glaucosaminate dehydratase (EC 4.2.1.26) has been developed. The method is based on the enzymatic dehydration of D-gluco-saminatie and the spectrophotomeric determination of the product, 2-keto-3-deoxy-D-gluconate, as its semicarbazone.
Y. Imanga, R. Iwamoto
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Grappling With the “Miracle” of Glucosamine
Journal of Orthopaedic & Sports Physical Therapy, 1999Glucosamine sulfate has been reported to reverse or stop the progression of osteoarthritis. Glucosamine is promoted as a nutritional supplement that rebuilds damaged articular surfaces and relieves pain as effectively as ibuprofen, but without serious side effects.
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