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Association of Mucin-Degrading Gut Microbiota and Dietary Patterns with Colonic Transit Time in Constipation: A Secondary Analysis of a Randomized Clinical Trial. [PDF]
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Annals of Pharmacotherapy, 1998
OBJECTIVE: To review the pharmacology and pharmacokinetics of glucosamine and critically evaluate currently available literature regarding its safety and efficacy. DATA SOURCE: A MEDLINE search was conducted between January 1965 and May 1997. Key words used in the search were osteoarthritis, osteoarthrosis, gonarthrosis, and glucosamine.
T S, Barclay, C, Tsourounis, G M, McCart
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OBJECTIVE: To review the pharmacology and pharmacokinetics of glucosamine and critically evaluate currently available literature regarding its safety and efficacy. DATA SOURCE: A MEDLINE search was conducted between January 1965 and May 1997. Key words used in the search were osteoarthritis, osteoarthrosis, gonarthrosis, and glucosamine.
T S, Barclay, C, Tsourounis, G M, McCart
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Glucosamine and Chondroitin Sulfate [PDF]
Rheumatic Disease Clinics of North America, 2011 Glucosamine and chondroitin sulfate, components of normal cartilage that are marketed as dietary supplements in the United States, have been evaluated for their potential role in the treatment of osteoarthritis. Due to claims of efficacy, increased prevalence of osteoarthritis, and a lack of other effective therapies, there has been substantial ...
Daniel O. Clegg +2 more
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Glucosamine and osteoarthritis [PDF]
Future Rheumatology, 2006 Osteoarthritis is the most common form of arthritis and is commonly associated with significant disability. Glucosamine is widely used by patients with osteoarthritis as a nutriceutical in the USA and as a pharmaceutical in Europe. The efficacy of oral glucosamine, with regard to both symptom and disease modification in patients with osteoarthritis ...
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Medical Hypotheses, 1997
Amphiregulin and transforming growth factor-alpha, agonists for the epidermal growth factor receptor, are the major autocrine growth factors for cultured keratinocytes, and their substantial overexpression in psoriatic lesions suggests that they are crucial to the basal hyperplasia that characterizes psoriasis. Amphiregulin binds to heparin and related
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Amphiregulin and transforming growth factor-alpha, agonists for the epidermal growth factor receptor, are the major autocrine growth factors for cultured keratinocytes, and their substantial overexpression in psoriatic lesions suggests that they are crucial to the basal hyperplasia that characterizes psoriasis. Amphiregulin binds to heparin and related
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2003
In the 1950s, in vitro studies of glucosamine demonstrated its potential to increase fibroblast production of collagen and mucopolysaccharides. These findings led to studies of glucosamine for the treatment of osteoarthritis (OA) in humans, first with an injectable product, and then with oral supplementation (McCarty, 1994).
Timothy S. Tracy, Melanie Johns Cupp
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In the 1950s, in vitro studies of glucosamine demonstrated its potential to increase fibroblast production of collagen and mucopolysaccharides. These findings led to studies of glucosamine for the treatment of osteoarthritis (OA) in humans, first with an injectable product, and then with oral supplementation (McCarty, 1994).
Timothy S. Tracy, Melanie Johns Cupp
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Exhaustive Methylation of Glucosamine
Journal of Pharmaceutical Sciences, 1961A reported synthesis of a glucosamine quaternary derivative was investigated by chemical and infrared spectra methods. Under the conditions reported the glucosamine was found to become degraded and tetramethylammonium iodide was formed.
Bernard Ecanow +2 more
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GLUCOSAMINE IN THE TREATMENT OF OSTEOARTHRITIS
Rheumatic Disease Clinics of North America, 2000Glucosamine sulfate, a constituent of cartilage, is evaluated for the treatment of osteoarthritis. Available data suggest that glucosamine decreases pain and improves function in osteoarthritis. Most of the glucosamine studies have methodological flaws or used parenteral formulations, making their data difficult to extrapolate into clinical practice ...
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The absolute configuration of glucosamine
Biochimica et Biophysica Acta (BBA) - General Subjects, 1967Abstract The absolute configuration of α- D -glucosamine hydrochloride has been determined by X-ray diffraction. The calculated Bijvoet differences in the intensity of the inverse reflections, arising out of the anomalous dispersion effect of the chlorine atom, agree well with those experimentally measured.
R. Chandrasekaran +2 more
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Enzymatic Microdetermination of D-Glucosaminate with D-Glucosaminate Dehydratase
Analytical Letters, 1982Abstract A simple spectrophotometric method for the dectermination of D-glucosaminate with bacterial D-glaucosaminate dehydratase (EC 4.2.1.26) has been developed. The method is based on the enzymatic dehydration of D-gluco-saminatie and the spectrophotomeric determination of the product, 2-keto-3-deoxy-D-gluconate, as its semicarbazone.
Y. Imanga, R. Iwamoto
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