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Glucosamine and osteoarthritis [PDF]
Future Rheumatology, 2006 Osteoarthritis is the most common form of arthritis and is commonly associated with significant disability. Glucosamine is widely used by patients with osteoarthritis as a nutriceutical in the USA and as a pharmaceutical in Europe. The efficacy of oral glucosamine, with regard to both symptom and disease modification in patients with osteoarthritis ...
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2003
In the 1950s, in vitro studies of glucosamine demonstrated its potential to increase fibroblast production of collagen and mucopolysaccharides. These findings led to studies of glucosamine for the treatment of osteoarthritis (OA) in humans, first with an injectable product, and then with oral supplementation (McCarty, 1994).
Timothy S. Tracy, Melanie Johns Cupp
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In the 1950s, in vitro studies of glucosamine demonstrated its potential to increase fibroblast production of collagen and mucopolysaccharides. These findings led to studies of glucosamine for the treatment of osteoarthritis (OA) in humans, first with an injectable product, and then with oral supplementation (McCarty, 1994).
Timothy S. Tracy, Melanie Johns Cupp
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Medical Hypotheses, 1997
Amphiregulin and transforming growth factor-alpha, agonists for the epidermal growth factor receptor, are the major autocrine growth factors for cultured keratinocytes, and their substantial overexpression in psoriatic lesions suggests that they are crucial to the basal hyperplasia that characterizes psoriasis. Amphiregulin binds to heparin and related
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Amphiregulin and transforming growth factor-alpha, agonists for the epidermal growth factor receptor, are the major autocrine growth factors for cultured keratinocytes, and their substantial overexpression in psoriatic lesions suggests that they are crucial to the basal hyperplasia that characterizes psoriasis. Amphiregulin binds to heparin and related
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Enzymatic Microdetermination of D-Glucosaminate with D-Glucosaminate Dehydratase
Analytical Letters, 1982Abstract A simple spectrophotometric method for the dectermination of D-glucosaminate with bacterial D-glaucosaminate dehydratase (EC 4.2.1.26) has been developed. The method is based on the enzymatic dehydration of D-gluco-saminatie and the spectrophotomeric determination of the product, 2-keto-3-deoxy-D-gluconate, as its semicarbazone.
Y. Imanga, R. Iwamoto
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Chemical Communications, 2017
An easily synthesizable probe has been employed for dual mode sensing of glucosamine in pure water. The method was also applied for glucosamine estimation in blood serum samples and pharmaceutical tablets.
N. Dey, S. Bhattacharya
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An easily synthesizable probe has been employed for dual mode sensing of glucosamine in pure water. The method was also applied for glucosamine estimation in blood serum samples and pharmaceutical tablets.
N. Dey, S. Bhattacharya
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GLUCOSAMINE IN THE TREATMENT OF OSTEOARTHRITIS
Rheumatic Disease Clinics of North America, 2000Glucosamine sulfate, a constituent of cartilage, is evaluated for the treatment of osteoarthritis. Available data suggest that glucosamine decreases pain and improves function in osteoarthritis. Most of the glucosamine studies have methodological flaws or used parenteral formulations, making their data difficult to extrapolate into clinical practice ...
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Exhaustive Methylation of Glucosamine
Journal of Pharmaceutical Sciences, 1961A reported synthesis of a glucosamine quaternary derivative was investigated by chemical and infrared spectra methods. Under the conditions reported the glucosamine was found to become degraded and tetramethylammonium iodide was formed.
Bernard Ecanow +2 more
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Grappling With the “Miracle” of Glucosamine
Journal of Orthopaedic & Sports Physical Therapy, 1999Glucosamine sulfate has been reported to reverse or stop the progression of osteoarthritis. Glucosamine is promoted as a nutritional supplement that rebuilds damaged articular surfaces and relieves pain as effectively as ibuprofen, but without serious side effects.
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Journal of Agricultural and Food Chemistry, 2015
Cichoric acid, a caffeic acid derivative found in Echinacea purpurea, basil, and chicory, has been reported to have bioactive effects, such as anti-inflammatory, antioxidant, and preventing insulin resistance.
Di Zhu +4 more
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Cichoric acid, a caffeic acid derivative found in Echinacea purpurea, basil, and chicory, has been reported to have bioactive effects, such as anti-inflammatory, antioxidant, and preventing insulin resistance.
Di Zhu +4 more
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Hyperglycemic effect of glucosamine
American Journal of Physiology-Legacy Content, 1962The injection of large amounts of glucosamine into either alligators or rats increased the plasma glucose level to a height as great as that found in severe diabetes. Galactosamine and N-acetylglucosamine were inactive in this respect. Since glucosamine was not found to increase plasma lactic acid in either the alligator or rat or to decrease liver ...
Thomas Hernandez, Roland A. Coulson
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