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GLUCOSE‐6‐PHOSPHATE DEHYDROGENASE DEFICIENCY [PDF]

British Journal of Haematology, 1970
It has long been recognized that certain ordinarily salutary drugs may produce an acute hemolytic anemia in some susceptible individuals. The 8-aminoquinoline antimalarial, pamaquine (plasmoquine), was such a medication. It was the investigation of the hemolytic effect of pamaquine and its derivatives which led to the recognition that hereditary red ...
Jane F. Desforges, Ernest Beutler
openaire   +5 more sources

Glucose-6-Phosphate Dehydrogenase Deficiency [PDF]

Hematology/Oncology Clinics of North America, 2016
AbstractGlucose 6-phosphate dehydrogenase (G6PD) deficiency is 1 of the commonest human enzymopathies, caused by inherited mutations of the X-linked gene G6PD. G6PD deficiency makes red cells highly vulnerable to oxidative damage, and therefore susceptible to hemolysis.
Lucio Luzzatto, Mwashungi Ally, Rosario Notaro   +2 more
semanticscholar   +5 more sources

Glucose-6-Phosphate Dehydrogenase deficiency presented with convulsion: a rare case

Hematology Reports, 2014
Red blood cells carry oxygen in the body and Glucose-6-Phosphate Dehydrogenase protects these cells from oxidative chemicals. If there is a lack of Glucose-6-Phosphate Dehydrogenase, red blood cells can go acute hemolysis.
Alparslan Merdin, Fatma Avci, Nihal Guzelay   +2 more
doaj   +3 more sources

The association between glucose 6-phosphate dehydrogenase (G6PD) deficiency and attention deficit/hyperactivity disorder (ADHD) [PDF]

Eur Psychiatry
Krone B.
europepmc   +3 more sources

Is glucose-6-phosphate dehydrogenase deficiency associated with COVID-19 infection, severity, and death? A cohort study from the Brazilian Amazon. [PDF]

PLoS One
Dias ALB, Nascimento JR, Brito-Sousa JD, Sartim MA, da Silva KF, Silva-Neto AV, Dos Santos Mouta G, da Silva Balieiro PC, Baia-da-Silva DC, Almeida-Val F, de Melo GC, Sampaio VS, Lacerda M, Monteiro W.   +13 more
europepmc   +3 more sources

Ischemic Priapism Associated with Glucose-6-phosphate Dehydrogenase Deficiency: A Case Report [PDF]

Oman Medical Journal
Ischemic priapism is a male urologic emergency. Most cases have been linked to genetic conditions such as sickle cell disease and (much more rarely) glucose-6-phosphate dehydrogenase deficiency, and the use of certain drugs. Here, we report the case of a
Noor Nabi Junejo, Muhammad Humza Kamal, Shahid Aquil, Joseph Kunju Mathew   +3 more
doaj   +2 more sources

The Multiple Roles of Glucose-6-Phosphate Dehydrogenase in Tumorigenesis and Cancer Chemoresistance

Life, 2022
The pentose phosphate pathway (PPP) is a branch from glycolysis that begins from glucose-6-phosphate (G6P) and ends up with fructose-6-phosphate (F6P) and glyceraldehyde-3-phosphate (GADP).
Jiaqi Song, Huanran Sun, Shuai Zhang, Changliang Shan   +3 more
semanticscholar   +1 more source

Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance Melanoma metastasis is limited by oxidative stress. Cells that enter the blood experience high levels of reactive oxygen species and usually die of ferroptosis.
A. Aurora, Vishal Khivansara, Ashley Leach, Jennifer G. Gill, Misty S. Martin-Sandoval, Chendong Yang, Stacy Kasitinon, Divya Bezwada, Alpaslan Tasdogan, Wen Gu, Thomas P Mathews, Zhiyu Zhao, R. Deberardinis, S. Morrison   +13 more
semanticscholar   +1 more source

Prevalence of glucose-6-phosphate dehydrogenase deficiency in India: An updated meta-analysis

, 2016
Pradeep Kumar, Upendra Yadav, Vandana Rai   +2 more
openalex   +2 more sources

Glucose-6-phosphate dehydrogenase deficiency [PDF]

Critical Reviews in Oncology/Hematology, 1995
Glucose-6-phosphate dehydrogenase (G6PD) is an X chromosome-linked enzyme and the key enzyme of the pentose phosphate pathway. The G6PD functions to reduce nicotinamide-adenine-dinucleotide phosphate (NADP) to a reduced form (NADPH), while it oxidizes glucosed-phosphate (G6P) in the hexose monophosphate shunt.
J G, Chang, T C, Liu
  +5 more sources