Dehydrogenation of the phosphonate analogue of glucose 6-phosphate by glucose 6-phosphate dehydrogenase [PDF]
6,7 -Dideoxy-α-D-gluco-heptose 7-phosphonic acid, the isosteric phosphonate analogue of glucose 6-phosphate, was synthesized in six steps from the readily available precursor benzyl 4,6-O-benzylidene-α-D-glucopyranoside. The analogue is a substrate for yeast glucose 6-phosphate dehydrogenase, showing Michaelis-Menten kinetics at pH7.5 and 8.0.
P R, Adams +3 more
openaire +2 more sources
Metabolic alterations during the growth of tumour spheroids [PDF]
Solid tumours undergo considerable alterations in their metabolism of nutrients in order to generate sufficient energy and biomass for sustained growth and proliferation.
A Yalcin +80 more
core +3 more sources
Glucose-6-Phosphate Dehydrogenase deficiency presented with convulsion: a rare case
Red blood cells carry oxygen in the body and Glucose-6-Phosphate Dehydrogenase protects these cells from oxidative chemicals. If there is a lack of Glucose-6-Phosphate Dehydrogenase, red blood cells can go acute hemolysis.
Alparslan Merdin +2 more
doaj +1 more source
Glucose-6-phosphate dehydrogenase deficiency in Nigerian children. [PDF]
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzymopathy and in Sub-Saharan Africa, is a significant cause of infection- and drug-induced hemolysis and neonatal jaundice.
Olatundun Williams +5 more
doaj +1 more source
Glucose-6-phosphate dehydrogenase deficiency [PDF]
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most commonly known inherited disorder in man, and is estimated to affect 400 million people worldwide.' The highest prevalence rates (with gene frequencies in the range of 5-25% are found in tropical Africa, the Middle East, tropical and sub-tropical Asia, some parts of the Mediterranean, and ...
openaire +2 more sources
Emerging role of the pentose phosphate pathway in hepatocellular carcinoma [PDF]
In recent years, there has been a revival of interest in metabolic changes of cancer cells as it has been noticed that malignant transformation and metabolic reprogramming are closely intertwined.
Columbano, Amedeo +2 more
core +2 more sources
UNDERINVESTIGATED ROLES OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE
The review examines certain aspects of the reaction catalyzed by glucose-6-phosphate dehydrogenase (G6PDH) in living organisms of different taxa, from bacteria to humans. Particular emphasis is put to the role of G6PDH in iron homeostasis and lipogenesis.
Dmytro Gospodaryov
doaj +1 more source
From meadows to milk to mucosa – adaptation of Streptococcus and Lactococcus species to their nutritional environments [PDF]
Lactic acid bacteria (LAB) are indigenous to food-related habitats as well as associated with the mucosal surfaces of animals. The LAB family Streptococcaceae consists of the genera Lactococcus and Streptococcus.
Adab, P. +12 more
core +13 more sources
Fulminant hemolysis in glucose‐6‐phosphate dehydrogenase deficiency
Key Clinical Message Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is an X‐linked disorder affecting some 400 million people worldwide. Though clinically silent, it may result in hemolysis on oxidative stress induced by drugs or infections.
Bushra Moiz, Sidra Asad Ali
doaj +1 more source
MOLECULAR BASIS OF G6PD DEFICIENCY: CURRENT STATUS AND ITS PERSPECTIVE [PDF]
Glucose-6-phosphate dehydrogenase is an essential enzyme to cell growth. Its deficiency of enzyme plays an important role in senescence and death signaling.
M. R. Noori-Daloii, M. Daneshpajooh
doaj +2 more sources

