Results 31 to 40 of about 352,162 (366)

Characterization of theThreshold for NAD(P)H:quinone Oxidoreductase Activity in Intact Sulforaphane-treated Pulmonary Arterial Endothelial Cells [PDF]

, 2011
Treatment of bovine pulmonary arterial endothelial cells in culture with the phase II enzyme inducer sulforaphane (5 μM, 24 h; sulf-treated) increased cell-lysate NAD(P)H:quinone oxidoreductase (NQO1) activity by 5.7 ± 0.6 (mean ± SEM)-fold, but intact ...
Bongard, Robert D., Gastonguay, Adam J., Krenz, Gary S., Lindemer, Brian J., Merker, Marilyn P., Williams, Carol L.   +5 more
core   +2 more sources

Use of primaquine and glucose-6-phosphate dehydrogenase deficiency testing: Divergent policies and practices in malaria endemic countries

PLoS Neglected Tropical Diseases, 2018
Primaquine is the only available antimalarial drug that kills dormant liver stages of Plasmodium vivax and Plasmodium ovale malarias and therefore prevents their relapse (‘radical cure’).
Judith Recht, E. Ashley, N. White
semanticscholar   +1 more source

Liver dehydrogenase levels in rainbow trout, Salmo gairdneri, fed cyclopropenoid fatty acids and aflatoxin B1

Journal of Lipid Research, 1973
Cyclopropenoid fatty acids in the diet of rainbow trout caused significant reductions in liver protein and activity of glucose-6-phosphate dehydrogenase, NADP-linked isocitrate dehydrogenase, lactate dehydrogenase, and malate dehydrogenase.
S.L. Taylor, M.W. Montgomery, D.J. Lee
doaj   +1 more source

Acquired Glucose-6-Phosphate Dehydrogenase Deficiency

Journal of Clinical Medicine, 2022
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a hereditary condition caused by mutations on chromosome X and is transmitted by a sex-linked inheritance. However, impairment of G6PD activity may result from biochemical mechanisms that are able to inhibit the enzyme in specific clinical conditions in the absence of a structural gene-level defect.
Giovanni Mario Pes, Maria Pina Dore
openaire   +2 more sources

Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator

Nature Communications, 2018
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, one of the most common human genetic enzymopathies, is caused by over 160 different point mutations and contributes to the severity of many acute and chronic diseases associated with oxidative stress ...
Sunhee Hwang, K. Mruk, S. Rahighi, Andrew G. Raub, Che-Hong Chen, L. Dorn, N. Horikoshi, S. Wakatsuki, James K. Chen, D. Mochly‐Rosen   +9 more
semanticscholar   +1 more source

Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle [PDF]

, 2016
The development of skeletal muscle insulin resistance is an early physiological defect, yet the intracellular mechanisms accounting for this metabolic defect remained unresolved. Here, we have examined the role of glucose-6-phosphate dehydrogenase (G6PDH)
Bruce, CR, Colgan, TD, Drummond, GR, Febbraio, MA, Greenfield, JR, Gregorevic, P, Henstridge, DC, Hoffman, NJ, Hong, YH, Iliades, P, Kingwell, BA, Kraakman, MJ, Lee-Young, RS, Lynch, GS, McConell, Glenn, Murphy, KT, Samocha-Bonet, D, Siebel, AL, Zivanovic, B   +18 more
core   +4 more sources

Kernicterus by glucose-6-phosphate dehydrogenase deficiency: a case report and review of the literature

Journal of Medical Case Reports, 2008
Introduction Glucose-6-phosphate dehydrogenase deficiency is an X-linked recessive disease that causes acute or chronic hemolytic anemia and potentially leads to severe jaundice in response to oxidative agents.
Cossio de Gurrola Gladys, Araúz Juan, Durán Elfilda, Aguilar-Medina Maribel, Ramos-Payán Rosalío, García-Magallanes Noemí, Pacheco Gerardo, Arámbula Meraz Eliakym   +7 more
doaj   +1 more source

Structural studies of glucose-6-phosphate and NADP+ binding to human glucose-6-phosphate dehydrogenase [PDF]

, 2005
Human glucose-6-phosphate dehydrogenase (G6PD) is NADP(+)-dependent and catalyses the first and rate-limiting step of the pentose phosphate shunt. Binary complexes of the human deletion mutant, DeltaG6PD, with glucose-6-phosphate and NADP(+) have been ...
Adams, MJ, Au, SWN, Gover, S, Kataka, M, Lam, VMS, Vandeputte-Rutten, S   +5 more
core   +1 more source

Evaluation of a Novel Quantitative Test for Glucose-6-Phosphate Dehydrogenase Deficiency: Bringing Quantitative Testing for Glucose-6-Phosphate Dehydrogenase Deficiency Closer to the Patient

American Journal of Tropical Medicine and Hygiene, 2018
. Glucose-6-phosphate dehydrogenase (G6PD) deficiency, a common genetic blood condition, can result in kernicterus at birth, and later in life as severe hemolysis on exposure to certain infections, foods, and drugs.
S. Pal, P. Bansil, G. Bancone, Sevan Hrutkay, M. Kahn, G. Gornsawun, P. Penpitchaporn, C. Chu, F. Nosten, G. Domingo   +9 more
semanticscholar   +1 more source

The Effects of Fenarimol and Methyl Parathion on Glucose 6-Phosphate Dehydrogenase Enzyme Activity in Rats

Türkiye Tarımsal Araştırmalar Dergisi, 2017
Fenarimol and methyl parathion are pesticides that have been used in agriculture for several years. These pesticides have significant effects on environmental and human health. Therefore, we investigated the effects of methyl parathion and fenarimol on
Ferda ARI, Egemen DERE, Hakan TOSUNOĞLU, İmren ALİOĞLU   +3 more
doaj   +1 more source