Results 91 to 100 of about 103,990 (298)

Homozygous ?- thalassemia with Glucose 6 phosphate dehydrogenase deficiency: A case report.

Mediterranean Journal of Hematology and Infectious Diseases, 2014
The thalassemias and glucose 6 phosphate dehydrogenase deficiency are among the most common disorders worldwide. The marked oxidative stress caused by ?-thalassemia, that is apparently incompatible with glucose 6 phosphate dehydrogenase deficiency was ...
Jitender Mohan Khunger, Rohit Kapoor, Rekha Singh, Monica Khunger, Renu Saxena   +4 more
doaj  

Fructose metabolism in Chromohalobacter salexigens: interplay between the Embden–Meyerhof–Parnas and Entner–Doudoroff pathways [PDF]

, 2019
Background The halophilic bacterium Chromohalobacter salexigens metabolizes glucose exclusively through the Entner–Doudoroff (ED) pathway, an adaptation which results in inefficient growth, with significant carbon overflow, especially at low salinity ...
Argandoña Bertrán, Montserrat, Bernal, Vicente, Borges, Nuno, Castaño Cerezo, Sara, Csonka, Laszlo N., Cánovas, Manuel, Gonçalves, Luís G., Goodner, Bradley W., Nieto Gutiérrez, Joaquín José, Pagán, Juan P., Pastor, José M., Reynolds, Kathryn A., Vargas Macías, Carmen   +12 more
core   +1 more source

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source

Prevalence of glucose-6-phosphate dehydrogenase deficiency in neonates in Egypt

Annals of Saudi Medicine, 2017
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder which causes neonatal jaundice in most cases, and under certain conditions, can cause a spectrum of hemolytic manifestations.
Soheir Abo Elella, Mahaa Tawfik, Naglaa Barseem, Wafaa Moustafa   +3 more
doaj   +1 more source

Metabolic Regulation of Epithelial to Mesenchymal Transition: Implications for Endocrine Cancer [PDF]

, 2019
York University ...
Bhattacharya, Debasmita, Scimè, Anthony
core   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Enhanced Eryptosis in Glucose-6-Phosphate Dehydrogenase Deficiency

Cellular Physiology and Biochemistry, 2021
Ghada Bouguerra, Khaoula Talbi, Nawel Trabelsi, Dorra Chaouachi, Imen Boudriga, Salem Abbès, Samia Menif   +6 more
doaj   +1 more source

Methemoglobinemia and Glucose-6-phosphate Dehydrogenase Deficiency in a Neonate

Indian Pediatrics Case Reports
Background: Methemoglobinemia is a condition where heme iron is oxidized from ferrous to ferric state, leading to hypoxia. Commonly due to drugs and toxins, it may rarely occur due to glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Saurabh Aggarwal, Shubham Garg, Mridu Jain Sehgal, Jagpreet Singh Bhatia   +3 more
doaj   +1 more source

Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator

Nature Communications, 2018
Glucose-6-phosphate dehydrogenase (G6PD) deficiency provides insufficient protection from oxidative stress, contributing to diverse human pathologies. Here, the authors identify a small molecule that increases the activity and/or stability of mutant G6PD
Sunhee Hwang, Karen Mruk, Simin Rahighi, Andrew G. Raub, Che-Hong Chen, Lisa E. Dorn, Naoki Horikoshi, Soichi Wakatsuki, James K. Chen, Daria Mochly-Rosen   +9 more
doaj   +1 more source