Results 131 to 140 of about 64,860 (226)
Abstract Developing protein interaction–based technologies such as biosensors requires a clear understanding of receptor‐target kinetics. Nanobodies, which are camelid‐derived single‐domain antibodies, are ideal biosensor receptors due to their high specificity, stability, and ease of production. During biosensor development, multiple nanobody variants
Escarlet Díaz‐Galicia +5 more
wiley +1 more source
How Salmonella Works Under Osmotic and Desiccation Stresses
ABSTRACT Salmonella remains one of the leading threats in foods with reduced water activity, where it can survive for long periods and cause outbreaks. Its persistence stems from a wide array of adaptive strategies shaped by the selective pressures imposed by low‐moisture foods.
Mayara Messias Oliveira +2 more
wiley +1 more source
Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers +16 more
wiley +1 more source
This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li +11 more
wiley +1 more source
ABSTRACT Although Doxorubicin (Dox) is an effective anticancer drug, it can cause severe cardiotoxicity. While several mechanisms have been proposed to explain Dox‐induced cardiomyopathy (DIC), strategies to prevent it remain limited. In previous research on isolated cardiomyocytes, we identified that Empagliflozin (EMPA), an antidiabetic drug ...
Akshi Malik +6 more
wiley +1 more source
Insulin Receptor Isoform Pattern in Aged Normal and Alzheimer's Human Cortex
In this study we asked (A) which antibodies accurately detect insulin receptors in human brain? Our data demonstrate that the three antibodies we have characterised work well but there is a hierarchy with 250 724 working well, PA5‐27334 working better and NBP‐12793 working best.
Catherine Webb‐Robinson +5 more
wiley +1 more source
Natural and Synthetic Metabolic Architectures
Metabolism yields function through architecture, not through isolated parts. This Perspective article discusses how design can move from components to connectivity and then to architectural regimes that account for space, time, and routing. The framework links understanding to engineering and helps explain why microbial engineering meets challenges ...
Pablo I. Nikel
wiley +1 more source
Whole-transcriptome Analysis of Fully Viable Energy Efficient Glycolytic-null Cancer Cells Established by Double Genetic Knockout of Lactate Dehydrogenase A/B or Glucose-6-Phosphate Isomerase. [PDF]
Mazzio E +6 more
europepmc +1 more source

