Results 161 to 170 of about 39,010 (190)

Glucose 6 phosphate isomerase as a diagnostic test in rheumatoid arthritis

Biochemical and Cellular Archives, 2022
Rheumatoid arthritis (RA) a chronic auto-immune condition. is characterized by inflammation that contributes to the deterioration of joints, bones, tendons and ligaments. Glucose-6-phosphate isomerase (G6PI) is one of the autoantigens against, which RA patients develop autoantibodies that have been found to circulate in serum and in synovial fluid of ...
Kareem R. J. Alzaidi, Manal K. Rasheed, Mohammed Hadi AI-Osami   +2 more
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A Novel Glucose 6-Phosphate Isomerase from Listeria monocytogenes

The Protein Journal, 2014
D-Arabinose 5-phosphate isomerases (APIs) catalyze the interconversion of D-ribulose 5-phosphate and D-arabinose 5-phosphate (A5P). A5P is an intermediate in the biosynthesis of 3-deoxy-D-manno-octulosonate (Kdo), an essential component of lipopolysaccharide, the lipopolysaccharide found in the outer membrane of Gram-negative bacteria.
David L, Cech, Pan-Fen, Wang, Melissa C, Holt, Victoria A, Assimon, Jeffrey M, Schaub, Tod P, Holler, Ronald W, Woodard   +6 more
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Purification and characterization of glucose-6-phosphate isomerase from Bacillus stearothermophilus

Archives of Biochemistry and Biophysics, 1971
Abstract Glucose-6-phosphate isomerase (EC 5.3.1.9) has been purified from Bacillus stearothermophilus to a state in which it is homogeneous, both ultracentrifugally and electrophoretically. The sedimentation coefficient ( s 20, w ) and molecular weight of the enzyme are 7.4S and 172,000. The enzyme exhibits a maximum activity at 70 °.
N, Muramatsu, Y, Noso
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Combined Erythrocyte Phosphohexose Isomerase and Glucose-6-Phosphate Dehydrogenase Deficiency

Human Heredity, 1973
Combined erythrocyte phosphohexose isomerase (PHI) and glucose-6-phosphate dehydrogenase (G6PD) deficiency without hemolytic crisis is reported in a Thai family. The propositus (a male), heterozygous for PHI deficiency and hemizygous for G6PD deficiency, has a PHI activity of about half of the normal.
N, Sanpitak, Y, Supalert, L, Chayutimonkul, G, Flatz   +3 more
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Revisit of autoimmunity to glucose-6-phosphate isomerase in experimental and rheumatoid arthritis

Modern Rheumatology, 2019
Rheumatoid arthritis (RA) is an inflammatory disorder characterized by synovial inflammation in multiple joints. Autoantibodies (Abs) are the hallmark of RA, and as disease-specific and diagnostic markers, rheumatoid factor and anti-citrullinated protein antibody (ACPA) are produced pre-clinically, but their pathogenic roles in RA remain elusive.
Isao, Matsumoto, Izumi, Kurata, Ayako, Ohyama, Hoshimi, Kawaguchi, Hiroshi, Ebe, Atsumu, Osada, Yuya, Kondo, Hiroto, Tsuboi, Takayuki, Sumida   +8 more
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Elevated Serum Glucose-6-Phosphate Isomerase Level in Patients with Knee Osteoarthritis

Clinical Laboratory, 2020
The present study aims to analyze the serum level of glucose 6-phosphate isomerase (GPI) in patients with knee osteoarthritis (KOA) and evaluate its value in the diagnosis of KOA.One hundred patients with confirmed KOA were selected and 100 healthy people in the same period were selected as the control group.
Xiaomeng, Ji, Weiwei, Bian
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Mouse glucose-6-phosphate isomerase and neuroleukin have identical 3′ sequences

Nature, 1988
Neuroleukin is a neurotrophic factor of relative molecular mass (Mr) 56,000 (56K) found in skeletal muscle, brain, heart and kidneys which supports the survival of embryonic spinal neurones, skeletal motor neurones and sensory neurones. Neuroleukin is also a lymphokine product of lectin-stimulated T cells and induces immunoglobulin secretion by ...
P, Faik, J I, Walker, A A, Redmill, M J, Morgan   +3 more
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Protein disulphide isomerase assisted folding of human glucose-6-phosphate dehydrogenase

Biochemical Society Transactions, 1995
Glucose 6-phosphate dehydrogenase (G6PD) plays a key role to maintain the redox state within the red cells. The molecular basis of human G6PD deficiency rely on the presence of point mutations along its 59.2 kDa subunit [l]. The intracellular active enzyme behave mostly as a homodimer.
F, Gomez-Gallego, A, Garrido-Pertierra, J M, Bautista   +2 more
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Specific activities of 6-phosphogluconate dehydrogenase, glucose-6-phosphate dehydrogenase and glucose-6-phosphate isomerase during Bufo bufo development

Biochimica et Biophysica Acta (BBA) - Enzymology, 1976
It has been suggested by some authors that during amphibian development, due to the higher glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activity compared to that of 6-phosphogluconate dehydrogenase (EC 1.1.1.43), 6-phosphogluconate could accumulate in the embryo tissues and regulate the channelling of glucose-6-phosphate into glycolysis.
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Crystallographic structure analysis of glucose 6-phosphate isomerase at 3·5 Å resolution

Journal of Molecular Biology, 1977
X-ray diffraction data sets have been measured to a nominal resolution of 3·5 A from crystals of porcine skeletal muscle glucose 6-phosphate isomerase using a four-circle diffractometer, and phase angles have been estimated by the method of isomorphous replacement with anomalous scattering measurements.
P J, Shaw, H, Muirhead
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