Results 181 to 190 of about 64,860 (226)

Glucose-6-phosphate isomerase deficiency

Best Practice and Research in Clinical Haematology, 2000
Most of the metabolic needs of erythrocytes are covered by glycolysis, the oxidative pentose phosphate pathway and the glutathione cycle. Hereditary enzyme deficiencies of all these pathways have been identified, among which glucose-6-phosphate isomerase (GPI) deficiency is the second most frequent erythroenzymopathy in glycolysis, being associated ...
Kugler, Wilfried, Lakomek, Max
exaly   +4 more sources

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Glucose - 6 - phosphate isomerase

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1981
Glucose-6-phosphate isomerase (EC 5 . 3 .1 .9) is a dimeric enzyme of molecular mass 132000 which catalyses the interconversion of D-glucose-6-phosphate and D-fructose- 6-phosphate. The crystal structure of the enzyme from pig muscle has been determined at a nominal resolution of 2.6 A. The structure is of the a/B type.
A, Achari, S E, Marshall, H, Muirhead, R H, Palmieri, E A, Noltmann   +4 more
openaire   +2 more sources

Suppression of glucose-6-phosphate-isomerase induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of glucose-6-phosphate-isomerase

Modern Rheumatology, 2017
To investigate the effects of transgenic rice seeds expressing the altered peptide ligand (APL) of human glucose-6-phosphate-isomerase (hGPI325-339) in mice model of GPI-induced arthritis (GIA).We generated transgenic rice expressing T-cell epitope of hGPI325-339 and APL12 contained in the seed endosperm.
Hiroto Tsuboi, Yuya Kondo, Yuhya Wakasa
exaly   +3 more sources

Cell age dependent decay of human erythrocytes glucose-6-phosphate isomerase

BBA - Proteins and Proteomics, 1989
Glucose-6-phosphate isomerase shows a biphasic decay pattern during red blood cell aging, which is very fast during the first part of cell's life span in circulation. This decay is not due to accumulation of inactive enzyme molecules, as shown by immunological studies, but is accompanied by the formation of secondary isozymes (i.e., chemically modified
Mauro Magnani
exaly   +4 more sources

A Novel Glucose 6-Phosphate Isomerase from Listeria monocytogenes

The Protein Journal, 2014
D-Arabinose 5-phosphate isomerases (APIs) catalyze the interconversion of D-ribulose 5-phosphate and D-arabinose 5-phosphate (A5P). A5P is an intermediate in the biosynthesis of 3-deoxy-D-manno-octulosonate (Kdo), an essential component of lipopolysaccharide, the lipopolysaccharide found in the outer membrane of Gram-negative bacteria.
David L, Cech, Pan-Fen, Wang, Melissa C, Holt, Victoria A, Assimon, Jeffrey M, Schaub, Tod P, Holler, Ronald W, Woodard   +6 more
openaire   +2 more sources

Anomerization of glucose 6-phosphate: Catalysis by phosphoglucose isomerase

Archives of Biochemistry and Biophysics, 1979
Abstract The anomerase (1-epimerase) activity of phosphoglucose isomerase ( d -glucose 6-phosphate ketol-isomerase EC 5.3.1.9) has been studied. The pH-Vmax profile, assayed by two different methods, shows a dependence on two ionizable groups in the enzyme with pK values of 7.0 and 9.3 at 0 °C.
K J, Schray, E E, Howell
openaire   +2 more sources

Phylogenetic analysis of the glucose-6-phosphate isomerase gene in Trypanosoma cruzi

Experimental Parasitology, 2006
Trypanosoma cruzi, the agent of Chagas disease, has a basically clonal population structure with rare hybridization events. The species is subdivided into six "Discrete Typing Units" called DTUs I, IIa-e, distributed into two major phylogenetic lineages, T. cruzi I and II (TC I and II).
Hélène Broutin, Michel Tibayrenc, Christian Barnabé   +2 more
exaly   +4 more sources

Diagnostic value of glucose-6-phosphate isomerase in rheumatoid arthritis

Clinica Chimica Acta, 2010
Although glucose-6-phosphate isomerase (G6PI), anti-G6PI antibodies and G6PI-containing immune complexes (G6PI-CIC) have proved high expression in patients with rheumatoid arthritis (RA), comprehensive evaluation of the G6PI-derived markers, G6PI antigen, anti-G6PI Abs, G6PI-CIC and G6PI mRNA, in the diagnosis of RA remains necessary.We measured G6PI ...
Lie Ying, Fan, Ming, Zong, Qiang, Wang, Lin, Yang, Li Shan, Sun, Qin, Ye, Yuan Yuan, Ding, Jian Wei, Ma   +7 more
openaire   +2 more sources

Mouse glucose-6-phosphate isomerase and neuroleukin have identical 3′ sequences

Nature, 1988
Neuroleukin is a neurotrophic factor of relative molecular mass (Mr) 56,000 (56K) found in skeletal muscle, brain, heart and kidneys which supports the survival of embryonic spinal neurones, skeletal motor neurones and sensory neurones. Neuroleukin is also a lymphokine product of lectin-stimulated T cells and induces immunoglobulin secretion by ...
P, Faik, J I, Walker, A A, Redmill, M J, Morgan   +3 more
openaire   +3 more sources

Combined Erythrocyte Phosphohexose Isomerase and Glucose-6-Phosphate Dehydrogenase Deficiency

Human Heredity, 1973
Combined erythrocyte phosphohexose isomerase (PHI) and glucose-6-phosphate dehydrogenase (G6PD) deficiency without hemolytic crisis is reported in a Thai family. The propositus (a male), heterozygous for PHI deficiency and hemizygous for G6PD deficiency, has a PHI activity of about half of the normal.
N, Sanpitak, Y, Supalert, L, Chayutimonkul, G, Flatz   +3 more
openaire   +2 more sources