Results 201 to 210 of about 64,860 (226)
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Glucose 6 phosphate isomerase as a diagnostic test in rheumatoid arthritis
Biochemical and Cellular Archives, 2022Rheumatoid arthritis (RA) a chronic auto-immune condition. is characterized by inflammation that contributes to the deterioration of joints, bones, tendons and ligaments. Glucose-6-phosphate isomerase (G6PI) is one of the autoantigens against, which RA patients develop autoantibodies that have been found to circulate in serum and in synovial fluid of ...
Kareem R. J. Alzaidi +2 more
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Biochimica et Biophysica Acta (BBA) - Enzymology, 1976
It has been suggested by some authors that during amphibian development, due to the higher glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activity compared to that of 6-phosphogluconate dehydrogenase (EC 1.1.1.43), 6-phosphogluconate could accumulate in the embryo tissues and regulate the channelling of glucose-6-phosphate into glycolysis.
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It has been suggested by some authors that during amphibian development, due to the higher glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activity compared to that of 6-phosphogluconate dehydrogenase (EC 1.1.1.43), 6-phosphogluconate could accumulate in the embryo tissues and regulate the channelling of glucose-6-phosphate into glycolysis.
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2015
A patient with combined deficiency of erythrocyte glucose phosphate isomerase (GPI) and glucose-6-phosphate dehydrogenase (G6PD) is presented. The propositus has persistent unconjugated hyperbilirubinemia. One of his two brothers exhibits the same rare enzymatic defect, but without any clinical symptoms.
I, Steiman +3 more
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A patient with combined deficiency of erythrocyte glucose phosphate isomerase (GPI) and glucose-6-phosphate dehydrogenase (G6PD) is presented. The propositus has persistent unconjugated hyperbilirubinemia. One of his two brothers exhibits the same rare enzymatic defect, but without any clinical symptoms.
I, Steiman +3 more
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Revisit of autoimmunity to glucose-6-phosphate isomerase in experimental and rheumatoid arthritis
Modern Rheumatology, 2019Rheumatoid arthritis (RA) is an inflammatory disorder characterized by synovial inflammation in multiple joints. Autoantibodies (Abs) are the hallmark of RA, and as disease-specific and diagnostic markers, rheumatoid factor and anti-citrullinated protein antibody (ACPA) are produced pre-clinically, but their pathogenic roles in RA remain elusive.
Isao, Matsumoto +8 more
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Blood Cells, Molecules, and Diseases, 2003
Glucosephosphate isomerase (GPI) deficiency in humans is an autosomal recessive disorder, which results in nonspherocytic hemolytic anemia of variable clinical expression. A 4-year-old female with severe congenital hemolytic anemia had low red cell GPI activity of 15.5 IU/g Hb (50% of normal mean) indicating GPI deficiency.
Julia L, Clarke +9 more
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Glucosephosphate isomerase (GPI) deficiency in humans is an autosomal recessive disorder, which results in nonspherocytic hemolytic anemia of variable clinical expression. A 4-year-old female with severe congenital hemolytic anemia had low red cell GPI activity of 15.5 IU/g Hb (50% of normal mean) indicating GPI deficiency.
Julia L, Clarke +9 more
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Anomalous phylogeny involving the enzyme glucose-6-phosphate isomerase
Journal of Molecular Evolution, 1992M W, Smith, R F, Doolittle
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Israel journal of medical sciences, 1984
A glucose-6-phosphate isomerase deficiency is described in an Arab boy suffering from chronic hemolytic anemia. The patient was probably true homozygous for the defect. The residual enzyme activity in his red blood cells (RBC) was approximately 30% of normal. The most striking enzyme abnormality observed was an extreme heat lability: upon incubation at
Rijksen, G +5 more
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A glucose-6-phosphate isomerase deficiency is described in an Arab boy suffering from chronic hemolytic anemia. The patient was probably true homozygous for the defect. The residual enzyme activity in his red blood cells (RBC) was approximately 30% of normal. The most striking enzyme abnormality observed was an extreme heat lability: upon incubation at
Rijksen, G +5 more
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Two interconvertible forms of glucose-6-phosphate isomerase in rat muscle.
Biochemistry and molecular biology international, 1993Chromatography of crude rat muscle extracts on CM-cellulose resulted in separation of glucose-6-phosphate isomerase (GPI) into two active peaks (designated types I and II in order of elution). Incubation of type I and type II at pH 6.0, 7.0, or 8.0 in the presence and absence of KCI revealed that one type of GPI is converted to the other type under ...
Y, Toyoda, I, Miwa, S, Ogiso, J, Okuda
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DNA sequence abnormalities in human glucose 6-phosphate isomerase deficiency
Human Molecular Genetics, 1993J I, Walker +4 more
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