Results 241 to 250 of about 98,446 (260)
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Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase.

Arthritis & Rheumatism, 2008
OBJECTIVE To clarify the glucose-6-phosphate isomerase (GPI)-specific CD4+ T cell lineage involved in GPI-induced arthritis and to investigate their pathologic and regulatory roles in the induction of the disease. METHODS DBA/1 mice were immunized with
K. Iwanami   +11 more
semanticscholar   +1 more source

Protein disulphide isomerase assisted folding of human glucose-6-phosphate dehydrogenase

Biochemical Society Transactions, 1995
Glucose 6-phosphate dehydrogenase (G6PD) plays a key role to maintain the redox state within the red cells. The molecular basis of human G6PD deficiency rely on the presence of point mutations along its 59.2 kDa subunit [l]. The intracellular active enzyme behave mostly as a homodimer.
Amando Garrido-Pertierra   +2 more
openaire   +3 more sources

Crystallographic structure analysis of glucose 6-phosphate isomerase at 3·5 Å resolution

Journal of Molecular Biology, 1977
X-ray diffraction data sets have been measured to a nominal resolution of 3·5 A from crystals of porcine skeletal muscle glucose 6-phosphate isomerase using a four-circle diffractometer, and phase angles have been estimated by the method of isomorphous replacement with anomalous scattering measurements.
Hilary Muirhead, Peter Shaw
openaire   +3 more sources

6-Phosphogluconate Dehydrogenase, Glucose-6-Phosphate Dehydrogenase, Glucose-6-Phosphate Isomerase, and Hexokinase Activity Ratios in Some Human Tumor Cytosols

Tumori Journal, 1978
The ratios of some key enzymatic activities of carbohydrate metabolism have been measured in human tumor cytosols. The activities of whole hexokinase (low Km, EC 2.7.1.1 and high Km, EC 2.7.1.2), 6-phosphogluconate dehydrogenase (EC 1.1.1.43), glucose-6-phosphate dehydrogenase (EC 1.1.1.49) and glucose-6-phosphate isomerase (EC 5.3.1.9) change ...
Martano C   +5 more
openaire   +3 more sources

Combined Glucose Phosphate Isomerase and Glucose-6-Phosphate Dehydrogenase Deficiency of Erythrocytes

2015
A patient with combined deficiency of erythrocyte glucose phosphate isomerase (GPI) and glucose-6-phosphate dehydrogenase (G6PD) is presented. The propositus has persistent unconjugated hyperbilirubinemia. One of his two brothers exhibits the same rare enzymatic defect, but without any clinical symptoms.
Irina Steiman   +3 more
openaire   +3 more sources

Specific activities of 6-phosphogluconate dehydrogenase, glucose-6-phosphate dehydrogenase and glucose-6-phosphate isomerase during Bufo bufo development

Biochimica et Biophysica Acta (BBA) - Enzymology, 1976
It has been suggested by some authors that during amphibian development, due to the higher glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activity compared to that of 6-phosphogluconate dehydrogenase (EC 1.1.1.43), 6-phosphogluconate could accumulate in the embryo tissues and regulate the channelling of glucose-6-phosphate into glycolysis.
openaire   +3 more sources

Potential endocrine function of the glycolytic enzyme glucose-6-phosphate isomerase during implantation

General and Comparative Endocrinology, 2004
Glucose-6-phosphate isomerase (GPI) is a glycolytic enzyme that also acts as autocrine motility factor, a secreted protein that stimulates tumor cell motility. We have shown that GPI is required for embryo implantation in the domestic ferret. Here, we tested the hypothesis that GPI is produced and secreted into the bloodstream by ferret luteal cells ...
Laura C. Schulz, Janice M. Bahr
openaire   +3 more sources

Proteomics analysis of asthenozoospermia and identification of glucose-6-phosphate isomerase as an important enzyme for sperm motility.

Journal of Proteomics, 2019
Yueshuai Guo   +12 more
semanticscholar   +1 more source

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