Results 51 to 60 of about 67,753 (222)

Glucose-6-phosphate isomerase deficiency

open access: yesBest Practice & Research Clinical Haematology, 2000
Most of the metabolic needs of erythrocytes are covered by glycolysis, the oxidative pentose phosphate pathway and the glutathione cycle. Hereditary enzyme deficiencies of all these pathways have been identified, among which glucose-6-phosphate isomerase (GPI) deficiency is the second most frequent erythroenzymopathy in glycolysis, being associated ...
Kugler, Wilfried, Lakomek, Max
openaire   +4 more sources

Metabolic flexibilities and vulnerabilities in the pentose phosphate pathway of the zoonotic pathogen Toxoplasma gondii.

open access: yesPLoS Pathogens, 2022
Metabolic pathways underpin the growth and virulence of intracellular parasites and are therefore promising antiparasitic targets. The pentose phosphate pathway (PPP) is vital in most organisms, providing a reduced form of nicotinamide adenine ...
Ningbo Xia   +7 more
doaj   +1 more source

The Mechanism of Starch Over-Accumulation in Chlamydomonas reinhardtii High-Starch Mutants Identified by Comparative Transcriptome Analysis

open access: yesFrontiers in Microbiology, 2017
The focus of this study was the mechanism of starch accumulation in Chlamydomonas reinhardtii high-starch mutants. Three C. reinhardtii mutants showing high-starch content were generated using gamma irradiation.
Kwang M. Koo   +10 more
doaj   +1 more source

The Allergenicity Potential of Edible Freshwater Fish

open access: yesJournal of Food and Pharmaceutical Sciences, 2023
A Freshwater fish is a popular type of fish consumed in Indonesia besides seawater fish. However, until now the most available information regarding the potential allergenicity of fish is only related to seawater fish.
Atika Hanum Falihah   +2 more
doaj   +1 more source

Effects of Macromolecular Crowding on the Refolding of Glucose- 6-phosphate Dehydrogenase and Protein Disulfide Isomerase [PDF]

open access: hybridJournal of Biological Chemistry, 2001
The effects of polysaccharide, polyethylene glycol, and protein-crowding agents on the refolding of glucose-6-phosphate dehydrogenase (G6PDH) and protein disulfide isomerase have been examined. By increasing concentration during refolding, the reactivation yields of the two proteins decrease with the formation of soluble aggregates.
Jian Li, Sen Zhang, Chih-chen Wang
openalex   +5 more sources

Transcriptome reveals insights into biosynthesis of ginseng polysaccharides

open access: yesBMC Plant Biology, 2022
Background Ginseng polysaccharides, have been used to treat various diseases as an important active ingredient. Nevertheless, the biosynthesis of ginseng polysaccharides is poorly understood.
Xiaoxue Fang   +4 more
doaj   +1 more source

Thermodynamic and Kinetic Modeling of Co-utilization of Glucose and Xylose for 2,3-BDO Production by Zymomonas mobilis

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Prior engineering of the ethanologen Zymomonas mobilis has enabled it to metabolize xylose and to produce 2,3-butanediol (2,3-BDO) as a dominant fermentation product.
Chao Wu   +5 more
doaj   +1 more source

The Accumulation of Glucose 6-Phosphate from Glucose and Its Effect in an Escherichia coli Mutant Lacking Phosphoglucose Isomerase and Glucose 6-Phosphate Dehydrogenase

open access: hybridJournal of Biological Chemistry, 1968
Abstract When presented with glucose, an Escherichia coli mutant lacking both phosphoglucose isomerase and glucose 6-phosphate dehydrogenase accumulated, internally, high concentrations (approximately 50 mm) of glucose 6-phosphate. It also accumulated glucose in polysaccharide form. Other metabolism of glucose, if any, was very restricted.
D G Fraenkel
openalex   +4 more sources

Phosphoglucose Isomerase Plays a Key Role in Sugar Homeostasis, Stress Response, and Pathogenicity in Aspergillus flavus

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Aspergillus flavus is one of the important human and plant pathogens causing not only invasive aspergillosis in immunocompromised patients but also crop contamination resulting from carcinogenic aflatoxins (AFs).
Yao Zhou   +14 more
doaj   +1 more source

Glucose 6-Phosphate Accumulates via Phosphoglucose Isomerase Inhibition in Heart Muscle [PDF]

open access: yesCirculation Research, 2020
Rationale: Metabolic and structural remodeling is a hallmark of heart failure. This remodeling involves activation of the mTOR (mammalian target of rapamycin) signaling pathway, but little is known on how intermediary metabolites are integrated as metabolic signals.
Anja Karlstaedt   +3 more
openaire   +3 more sources

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