Results 81 to 90 of about 39,010 (190)
Glucose-6-phosphate isomerase deficiency results in mTOR activation, failed translocation of lipin 1α to the nucleus and hypersensitivity to glucose: Implications for the inherited glycolytic disease [PDF]
, 2011 Inherited glucose-6-phosphate isomerase (GPI) deficiency is the second most frequent glycolytic erythroenzymopathy in humans. Patients present with non-spherocytic anemia of variable severity and with neuromuscular dysfunction.
Jorge F. Haller +9 more
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Pediatric Hematology Oncology JournalBackground: There is a lack of literature on the role of splenectomy in hemolytic anemias due to glucose-6-phosphate isomerase (GPI) deficiency. GPI deficiency is a rare red blood cell (RBC) enzymopathy of the glycolytic pathway. Most present with severe
Abhilasha Sampagar +5 more
doaj +1 more source
Ribose-5-phosphate isomerase A regulates hepatocarcinogenesis via PP2A and ERK signaling [PDF]
, 2017 The deregulated nonoxidative pentose phosphate pathway (PPP) is known to promote oncogenesis, but the molecular mechanism remains unknown. Here, we report that human ribose-5-phosphate isomerase A (RPIA) plays a role in human hepatocellular carcinoma ...
楊銘淇 +1 more
core +1 more source
Biomolecules, 2019 The cupin-type phosphoglucose isomerase (PfPGI) from the hyperthermophilic archaeon Pyrococcus furiosus catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
Kalyanasundaram Subramanian +13 more
doaj +1 more source
ON THE MECHANISM OF GLUCOSE-6-PHOSPHATE OXIDATION IN CELL-FREE EXTRACTS OF XANTHOMONAS PHASEOLI (XP8) [PDF]
, 1958 Extracts of the plant pathogenic organism Xanthomonas phaseoli contain both TPN- and DPN-linked glucose-6-phosphate dehydrogenases as well as a DPN-specific glyceraldehyde phosphate dehydrogenase.
H. Katznelson, R. M. Hochster
core +1 more source
Molecular Biology and Evolution, 2007 Glucose-6-phosphate isomerase (GPI) has an essential function in both catabolic glycolysis and anabolic gluconeogenesis and is universally distributed among Eukaryotes, Bacteria, and some Archaea. In addition to the cytosolic GPI, land plant chloroplasts harbor a nuclear encoded isoenzyme of cyanobacterial origin that is indispensable for the oxidative
Carina, Grauvogel +2 more
openaire +2 more sources
Genetic studies with a phosphoglucose isomerase mutant of Saccharomyces cerevisiae [PDF]
, 1977 A mutation pgi1 in the yeast Saccharomyces cerevisiae conferring deficiency of the glycolytic enzyme glucose 6-phosphate isomerase is characterised genetically. The mutation segregates 2+:2- in tetrads from diploids heterozygous for the mutant phenotype.
Maitra, P. K., Lobo, Zita
core +1 more source
Applied Biological ChemistryCurrent therapeutic approaches for colorectal cancer (CRC) face significant limitations, including drug resistance, adverse effects, and high costs.
Kyunghee Lee +6 more
doaj +1 more source
6-BA Delays the Senescence of Postharvest Cabbage Leaves by Inhibiting Respiratory Metabolism
Foods6-BA, a small molecule compound of cytokinins, has been proven to delay leaf senescence in different species, including Chinese flowering cabbage; however, its specific mechanism remains relatively unknown. In this study, the application of external 6-BA
Cimei Wang +7 more
doaj +1 more source
PLoS ONE, 2015 Cannabinoid CB1 receptors peripherally modulate energy metabolism. Here, we investigated the role of CB1 receptors in the expression of glucose/pyruvate/tricarboxylic acid (TCA) metabolism in rat abdominal muscle.
Sergio Arrabal +16 more
doaj +1 more source