Results 121 to 130 of about 590,245 (355)

Somatostatin blockade of acute and chronic stimuli of the endocrine pancreas and the consequences of this blockade on glucose homeostasis. [PDF]

, 1975
Elliott W. Chideckel, Jerry P. Palmer, Donna J. Koerker, J. Ensinck, Monica Davidson, Charles J. Goodner   +5 more
openalex   +1 more source

A role for von Hippel-Lindau protein in pancreatic beta-cell function. [PDF]

, 2009
ObjectiveThe Vhlh gene codes for the von Hippel-Lindau protein (VHL), a tumor suppressor that is a key player in the cellular response to oxygen sensing.
Cano, David A, Hebrok, Matthias, Puri, Sapna   +2 more
core  

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

Glucose homeostasis during the perinatal period in normal rats and rats with a glycogen storage disorder. [PDF]

, 1981
Kevin R. Gain, R. S. Malthus, Colin Watts   +2 more
openalex   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Does brown adipose tissue have a role to play in glucose homeostasis? [PDF]

, 1989
Michael A. Cawthorne
openalex   +1 more source

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source

Hepatic Dyrk1b impairs systemic glucose homeostasis by modulating Wbp2 expression in a kinase activity-dependent manner

Heliyon
Patients with gain-of-function mutations of Dyrk1b have higher fasting blood glucose (FBG) levels. However, the role of Dyrk1b in glucose metabolism is not fully elucidated.
Lianju Li, Yaoyu Zou, Chongrong Shen, Na Chen, Muye Tong, Ruixin Liu, Jiqiu Wang, Guang Ning   +7 more
doaj  

A single extra copy of Down syndrome critical region 1–4 results in impaired hepatic glucose homeostasis

Molecular Metabolism, 2019
Objectives: During fasting, hepatic gluconeogenesis is induced to maintain energy homeostasis. Moreover, abnormal dysregulation of hepatic glucose production is commonly observed in type 2 diabetes.
Dong Soo Seo, Gia Cac Chau, Kwan-Hyuck Baek, Sung Hee Um   +3 more
doaj  

IDOL regulates systemic energy balance through control of neuronal VLDLR expression. [PDF]

, 2019
Liver X receptors limit cellular lipid uptake by stimulating the transcription of Inducible Degrader of the LDL Receptor (IDOL), an E3 ubiquitin ligase that targets lipoprotein receptors for degradation.
Ahn, In Sook, Ahnmark, Andrea, Althage, Magnus, Andersén, Harriet, Arneson, Douglas V, Bjursell, Mikael, Bohlooly-Y, Mohammad, Boyd, Helen, Calkin, Anna C, Carreras, Alba, Cole, Tracy A, Correa, Stephanie M, Diamante, Graciel, Eliasson, Pernilla, Gao, Jie, Hong, Cynthia, Kim, Jason, Lee, Richard, Lee, Stephen D, Lindén, Daniel, Massa, Megan G, Maxvall, Ingela, Porritt, Michelle, Priest, Christina, Rajbhandari, Prashant, Seeliger, Frank, Tontonoz, Peter, van Veen, J Edward, Yang, Xia, Åkerblad, Peter   +29 more
core