Results 231 to 240 of about 590,245 (355)

Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian, Siya Dai, Chunyi Guo, Wenjun Wang, Jiajia Pang, Yichen Shen, Mingyuan Xu, Jie Hu, Wenguo Cui, Xiaoming Sun, Jinghong Xu   +10 more
wiley   +1 more source

Nesfatin-1 as a crucial mediator of glucose homeostasis in the reptile, Hemidactylus flaviviridis. [PDF]

Sci Rep
Dotania K, Tripathy M, Rai U.
europepmc   +1 more source

Interleukin-6 Is a Novel Factor Mediating Glucose Homeostasis During Skeletal Muscle Contraction [PDF]

, 2004
Mark A. Febbraio, Natalie Hiscock, Massimo Sacchetti, Christian P. Fischer, Bente Klarlund Pedersen   +4 more
openalex   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Gestational saccharin consumption disrupts gut-brain axis glucose homeostasis control in adolescent offspring rats in a sex-dependent manner. [PDF]

Biol Sex Differ
Pacheco-Sánchez B, Melgar-Locatelli S, López-Merchán R, Benítez-Marín MJ, Blasco-Alonso M, González-Mesa E, Tovar R, Rubio P, Suárez J, Sanjuan C, de Fonseca FR, Alén F, de Ceglia M, Rivera P.   +13 more
europepmc   +1 more source

Leptin and Leptin Receptor Gene Polymorphisms and Changes in Glucose Homeostasis in Response to Regular Exercise in Nondiabetic Individuals [PDF]

, 2004
Timo A. Lakka, Tuomo Rankinen, S. John Weisnagel, Marie‐Christine Chagnon, Hanna-Maaria Lakka, Olavi Ukkola, Normand G. Boulé, Treva Rice, Arthur S. Leon, James S. Skinner, Jack H. Wilmore, D. C. Rao, Richard N. Bergman, Claude Bouchard   +13 more
openalex   +1 more source

Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets

Advanced Science, EarlyView.
This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu, Peng Peng, Yi‐Ning Wang, Mao‐Yang He, Shuang He, Chen‐Tao Jin, Liu Yang, Xi Wang, Jia‐Xi Zheng, Jie Gao, Cheng‐Ran Xu   +10 more
wiley   +1 more source

Hepatic CCAAT/Enhancer Binding Protein α Mediates Induction of Lipogenesis and Regulation of Glucose Homeostasis in Leptin-Deficient Mice [PDF]

, 2004
Kimihiko Matsusue, Oksana Gavrilova, Gilles Lambert, H Bryan Brewer, Jerrold M. Ward, Yusuke Inoue, Derek LeRoith, Frank J. Gonzalez   +7 more
openalex   +1 more source

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

Advanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang, Hui Wang, Yingna Li, Jing Lu, Xiaolei Tang, Dan Yang, Manying Wang, Daqing Zhao, Fangbing Liu, Shuai Zhang, Liwei Sun   +10 more
wiley   +1 more source

Glucose Homeostasis Improvement After Single Anastomosis Duodenojejunal Bypass with Sleeve Gastrectomy in Goto-Kakizaki Rats. [PDF]

Obes Surg
Melone S, Fernandez-Cebrian JM, Amores M, Lopez-Tofiño Y, Perez-Fernandez E, Garcia-Garcia E, Acedo JM, Guijarro C, Cortijo SM, Abalo R, Pazos MR.   +10 more
europepmc   +1 more source