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Evaluation of Glucose Homeostasis
Current Protocols in Molecular Biology, 2007AbstractObesity and dyslipidemia are often found in association with insulin resistance (IR). These components combined with hypertension characterize the most common endocrine disorder in humans, the metabolic syndrome. Thus, in addition to profiling body weight evolution and lipid metabolites, glucose tolerance (a reflection of IR) and insulin ...
Carmen Argmann+3 more
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Glucose homeostasis in the newborn puppy [PDF]
THE ABSENCE of a prompt physiological response to low blood sugar frequently observed in the human newborn in the initial hours after birth remains an enima. 1-4 Previous studies have indicated that this hypoglycemic phase is unlikely to be due to functional hyperinsulinism in the normal infant, since intravenous (I.V.) glucose tolerance tests have ...
Robert E. Schwartz+2 more
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Neuroscience of glucose homeostasis
2014Plasma glucose concentrations are homeostatically regulated and maintained within strict boundaries. Several mechanisms are in place to increase glucose output when glucose levels in the circulation drop as a result of glucose utilization, or to decrease glucose output and increase tissue glucose uptake to prevent hyperglycemia.
Andries Kalsbeek+2 more
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The American Journal of Digestive Diseases, 1955
The diagnosis of functional hyperinsulinism would be made more frequently if the test for that condition were made more reliable and less confusing. It is proposed that the test be called “the glucose homeostasis test” rather than the currently used expression, “six hour glucose tolerance test” because the former term is actually what is determined ...
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The diagnosis of functional hyperinsulinism would be made more frequently if the test for that condition were made more reliable and less confusing. It is proposed that the test be called “the glucose homeostasis test” rather than the currently used expression, “six hour glucose tolerance test” because the former term is actually what is determined ...
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Central Regulation of Glucose Homeostasis
Comprehensive Physiology, 2017ABSTRACTThe ability of the brain to directly control glucose levels in the blood independently of its effects on food intake and body weight has been known ever since 1854 when Claude Bernard, a French physiologist, discovered that lesioning the floor of the fourth ventricle in rabbits led to a rise of sugar in the blood.
Lynda M. Williams+5 more
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Erythrocytes and Glucose Homeostasis in Rats
Diabetes, 1989The capacity of erythrocytes to modify their glycogen stores to compensate for changes in glucose concentration in plasma was studied. Experiments in vitro and in vivo demonstrated that erythrocytes absorbed and incorporated glucose into their glycogen stores when glucose concentration in the medium was high and liberated it when the concentration was ...
Verónica Guarner, Ramó Alvarez-Buylla
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Growth Hormone and Glucose Homeostasis
Hormone Research in Paediatrics, 2004Patients with active acromegaly are insulin-resistant and glucose-intolerant, whereas children with growth hormone (GH) deficiency (GHD) are insulin-sensitive and may develop fasting hypoglycaemia. Surprisingly, however, hypopituitary adults with unsubstituted GHD tend to be insulin-resistant, which may worsen during GH substitution.
Jørgensen, J.O.L.+6 more
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Neonatal Network, 2008
NEWBORNS ARE NURTURED in a uterine environment that provides and regulates their glucose supply. Once the umbilical cord is clamped and the maternal glucose supply is terminated, the neonate must begin glucose regulation. This regulation involves complex metabolic and hormonal pathways that may not be mature immediately after birth.
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NEWBORNS ARE NURTURED in a uterine environment that provides and regulates their glucose supply. Once the umbilical cord is clamped and the maternal glucose supply is terminated, the neonate must begin glucose regulation. This regulation involves complex metabolic and hormonal pathways that may not be mature immediately after birth.
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Glucose Homeostasis in the Newborn [PDF]
Measurements of insulin and glucagon secretion by pancreatic islets isolated from rat pups at various times after birth (0 hours to 15 days) indicate a progressive decline in basal insulin release and a progressive increase in basal glucagon release with age.
K. D. Buchanan+3 more
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Influence of Ageing on Glucose Homeostasis*
The Journal of Clinical Endocrinology & Metabolism, 1982The mechanism of age-related glucose intolerance was investigated by comparing forearm glucose uptake (FGU) during 100-g oral glucose tolerance tests (GTTs) in healthy men of different ages: group Y, 19–24 yr (n = 11); group M, 30–45 yr (n = 12); and group E, 70–83 yr (n = 9).
R.A. Jackson+8 more
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