Results 81 to 90 of about 111,943 (300)

Risk factors associated with postpartum glucose intolerance in gestational diabetes mellitus patients: A meta-analysis study

Pakistan Journal of Pharmaceutical Sciences
Women, especially those with a history of gestational diabetes mellitus (GDM), are at increased risk for abnormal glucose tolerance during and after pregnancy.
Naijun Chen, Qian Gao, Tingting Li
doaj   +1 more source

Challenges and Future Directives of Synthetic Biology in Engineering Plant–Microbe Partnerships for Sustainable Agriculture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma, Rebaona Reaobaka Molefe‐Madlaliso, Alaba Adewole Adebayo, Oghoye Priscilla Oyedoh, Godfrey Okainemen Oribhabor, Oluwaseun Emmanuel Shittu, Olubukola Oluranti Babalola   +6 more
wiley   +1 more source

Analysis of factors influencing glucose tolerance in Japanese patients with non-alcoholic fatty liver disease

Diabetology & Metabolic Syndrome, 2017
Background While the association of the prevalence of non-alcoholic fatty liver disease (NAFLD) with impaired glucose metabolism has been reported, the factors influencing glucose tolerance in NAFLD remain to be clarified.
Satoko Ohmi, Masafumi Ono, Hiroshi Takata, Seiki Hirano, Shogo Funakoshi, Yuichi Nishi, Kumiko Yoshimura, Eri Amano, Yoshio Terada, Toshiji Saibara, Shimpei Fujimoto   +10 more
doaj   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

The prevalence and risk factors for glucose intolerance in young Korean women with polycystic ovary syndrome [PDF]

, 2018
Insulin resistance and hyperinsulinemia play important roles in the pathogenesis of polycystic ovary syndrome (PCOS). In addition, some women with PCOS have been shown to have insulin secretory defects and can be predicted to be at an increased risk for ...
정혜원, 오지영, 성연아, 이혜진   +3 more
core   +1 more source

Effects of Trimethoprim on Three Previously Proposed Putative Biomarkers for OCT2/MATE‐Mediated Renal Drug‐Drug Interactions in Healthy Volunteers

Clinical Pharmacology &Therapeutics, EarlyView.
Regulatory agencies request the assessment of the potential of new drugs to cause transporter‐mediated drug‐drug interactions (DDI). This assessment can be improved by integrating endogenous biomarkers during drug development. Regarding the renal excretion of drugs such as metformin, the organic cation transporter (OCT) 2 and multidrug and toxin ...
Jana Picurová, Fabian Müller, Daniel Auge, Jörg König, Martin F. Fromm, Arne Gessner   +5 more
wiley   +1 more source

Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle [PDF]

, 2016
Objective: The development of skeletal muscle insulin resistance is an early physiological defect, yet the intracellular mechanisms accounting for this metabolic defect remained unresolved.
Hoffman, NJ (15694352), Iliades, P (15694364), Bruce, CR (15693713), McConell, GK (15515774), Gregorevic, P (15694163), Lynch, GS (15611264), Murphy, KT (15694355), Zivanovic, B (15694367), Colgan, TD (15694370), Kraakman, MJ (15694127), Febbraio, MA (15498638), Lee-Young, RS (15560264), Kingwell, BA (15526766), Hong, YH (15611255), Darren Henstridge (14738965), Greenfield, JR (15694373), Samocha-Bonet, D (15694358), Siebel, AL (15694361), Drummond, GR (15620900)   +18 more
core   +2 more sources

Alzheimer‐associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation

EMBO Molecular Medicine, 2015
Alzheimer's disease (AD) is associated with peripheral metabolic disorders. Clinical/epidemiological data indicate increased risk of diabetes in AD patients. Here, we show that intracerebroventricular infusion of AD‐associated Aβ oligomers (AβOs) in mice
Julia R Clarke, Natalia M Lyra e Silva, Claudia P Figueiredo, Rudimar L Frozza, Jose H Ledo, Danielle Beckman, Carlos K Katashima, Daniela Razolli, Bruno M Carvalho, Renata Frazão, Marina A Silveira, Felipe C Ribeiro, Theresa R Bomfim, Fernanda S Neves, William L Klein, Rodrigo Medeiros, Frank M LaFerla, Jose B Carvalheira, Mario J Saad, Douglas P Munoz, Licio A Velloso, Sergio T Ferreira, Fernanda G De Felice   +22 more
doaj   +1 more source

Changes in BMI, Duration of Overweight and Obesity, and Glucose Metabolism: 45 Years of Follow-up of a Birth Cohort [PDF]

, 2011
OBJECTIVE Long-term implications of childhood obesity and BMI change over the life course for risk of type 2 diabetes remain uncertain.
Claudia Thomas, Chris Power, Thomas, C, Power, C   +3 more
core   +1 more source

First National Expanded Genomic Newborn Screening Program in Qatar; A Pilot Study, Doha‐Heidelberg Collaboration

American Journal of Medical Genetics Part A, EarlyView.
Reem Alsulaiman, Sarah Okashah, Radja Messai Badji, Fatemeh Abbaszadeh, Yaser Alsarraj, Rehab Ali Abdulrahman, Noora Shahbeck, Thalib Moideen, Reema El Hassan, Fatima Al‐Hamaydeh, Einas Alkuwari, Said Ismail, Hilal Al‐ Rifai, Ghassan Abdoh, Christian P. Schaaf, Georg Hoffmann, Saad Al‐Kaabi, Wadha Al‐Muftah, Tawfeg Ben‐Omran   +18 more
wiley   +1 more source