KSR2 functions as a metabolic checkpoint for anti-PD-1 resistance by reprogramming glucose metabolism. [PDF]
Ge Y, Zhou Q, Zhang Q, Hu Y, Wang R.
europepmc +1 more source
Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li +22 more
wiley +1 more source
Associations between chrono-nutrition and glucose metabolism across levels of glucose impairment: The Maastricht Study. [PDF]
Chong MY +7 more
europepmc +1 more source
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu +12 more
wiley +1 more source
Glucose Metabolism Modulation as a Strategy to Enhance Cancer Radiotherapy. [PDF]
Gao S, Liu X, Chen S, Zhou P.
europepmc +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Effects of Collagen Hydrolysate-Based Protein Complexes on Physical Endurance, Glucose Metabolism, and Renal Function in Rats. [PDF]
Kurkin DV +4 more
europepmc +1 more source
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao +14 more
wiley +1 more source
Glucose Metabolism and Modeling Approaches in Pregnancy: From Dynamic Metabolic Tests to Continuous Glucose Monitoring. [PDF]
Morettini M +3 more
europepmc +1 more source

