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American Journal of Physiology-Legacy Content, 1964
Sixty normal mice were given single intravenous injections of glucose-U-C14. At varying times between 1 and 60 min following injection, either respiratory CO2 was collected or the animals were decapitated and blood, liver, and extrahepatic tissues were analyzed for glucose content and specific activity.
Baker, N, Huebotter, R
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Sixty normal mice were given single intravenous injections of glucose-U-C14. At varying times between 1 and 60 min following injection, either respiratory CO2 was collected or the animals were decapitated and blood, liver, and extrahepatic tissues were analyzed for glucose content and specific activity.
Baker, N, Huebotter, R
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The American Journal of Clinical Nutrition, 1980
Formation of CO2 from uniformly labeled 14C-glucose was measured in liver slices from uremic and normal rats. Both CO2 formation and lactate concentration were decreased in the uremic liver slices suggesting an inhibition of glucose oxidation. In addition, a net loss of glucose from the medium in the uremic preparation and a net gain in the normal ...
A, Quintanilla +3 more
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Formation of CO2 from uniformly labeled 14C-glucose was measured in liver slices from uremic and normal rats. Both CO2 formation and lactate concentration were decreased in the uremic liver slices suggesting an inhibition of glucose oxidation. In addition, a net loss of glucose from the medium in the uremic preparation and a net gain in the normal ...
A, Quintanilla +3 more
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Chlorpromazine and glucose metabolism
International Journal of Neuropharmacology, 1964Abstract Chlorpromazine in low doses (1.25 mgkg ) reduces the tolerance to glucose load for more than 24 hr. The effect is not related to changes in body temperature and is present in both adrenalectomized and adrenal demedullated rats. Part of this effect of chlorpromazine is related to changes in permeability as shown by the decreased ...
A, JORI, D, BERNARDI, S, GARATTINI
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2011
Activins, members of the TGF-β family, are multifunctional growth and differentiation factors. Activins regulate glucose/energy metabolism by promoting the differentiation of insulin-producing and -responsive cells, and regulating function of the differentiated cells.
Osamu, Hashimoto, Masayuki, Funaba
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Activins, members of the TGF-β family, are multifunctional growth and differentiation factors. Activins regulate glucose/energy metabolism by promoting the differentiation of insulin-producing and -responsive cells, and regulating function of the differentiated cells.
Osamu, Hashimoto, Masayuki, Funaba
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Canadian Journal of Biochemistry, 1970
Biotin enhances liver glucokinase in the diabetic rat. Experiments using inhibitors of protein and RNA synthesis suggest that this is mediated through de novo protein synthesis. Biotin treatment also increases the activities of other key glycolytic kinases, phosphofructokinase and pyruvate kinase, but has no effect on a bifunctional enzyme like ...
K, Dakshinamurti +2 more
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Biotin enhances liver glucokinase in the diabetic rat. Experiments using inhibitors of protein and RNA synthesis suggest that this is mediated through de novo protein synthesis. Biotin treatment also increases the activities of other key glycolytic kinases, phosphofructokinase and pyruvate kinase, but has no effect on a bifunctional enzyme like ...
K, Dakshinamurti +2 more
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2018
Otto Warburg observed a peculiar phenomenon in 1924, unknowingly laying the foundation for the field of cancer metabolism. While his contemporaries hypothesized that tumor cells derived the energy required for uncontrolled replication from proteolysis and lipolysis, Warburg instead found them to rapidly consume glucose, converting it to lactate [1 ...
Sminu, Bose, Anne, Le
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Otto Warburg observed a peculiar phenomenon in 1924, unknowingly laying the foundation for the field of cancer metabolism. While his contemporaries hypothesized that tumor cells derived the energy required for uncontrolled replication from proteolysis and lipolysis, Warburg instead found them to rapidly consume glucose, converting it to lactate [1 ...
Sminu, Bose, Anne, Le
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Glucose metabolism and catecholamines
Critical Care Medicine, 2007Until now, catecholamines were the drugs of choice to treat hypotension during shock states. Catecholamines, however, also have marked metabolic effects, particularly on glucose metabolism, and the degree of this metabolic response is directly related to the beta2-adrenoceptor activity of the individual compound used.
Eberhard, Barth +7 more
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Glucose metabolism in fish: a review
Journal of Comparative Physiology B, 2012Teleost fishes represent a highly diverse group consisting of more than 20,000 species living across all aquatic environments. This group has significant economical, societal and environmental impacts, yet research efforts have concentrated primarily on salmonid and cyprinid species.
Polakof, Sergio +3 more
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Current Opinion in Cell Biology, 2006
The first identified biochemical hallmark of tumor cells was a shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis. We now know that much of this metabolic conversion is controlled by specific transcriptional programs. Recent studies suggest that activation of the hypoxia-inducible factor (HIF) is a common consequence of a ...
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The first identified biochemical hallmark of tumor cells was a shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis. We now know that much of this metabolic conversion is controlled by specific transcriptional programs. Recent studies suggest that activation of the hypoxia-inducible factor (HIF) is a common consequence of a ...
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2014
Glucose is the main substrate for energy metabolism of the brain, and the regional cerebral metabolic rate is directly related to regional brain activity. Therefore, the measurement of regional glucose metabolism is of great importance for the assessment of regional normal function and of pathological changes.
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Glucose is the main substrate for energy metabolism of the brain, and the regional cerebral metabolic rate is directly related to regional brain activity. Therefore, the measurement of regional glucose metabolism is of great importance for the assessment of regional normal function and of pathological changes.
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